9PFL
Crystal structure of human 15-PGDH in complex with small molecule compound 1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | polymer | 255 | 27754.9 | 2 | UniProt (P15428) Pfam (PF00106) | Homo sapiens (human) | 15-PGDH,Eicosanoid/docosanoid dehydrogenase [NAD(+)],Prostaglandin dehydrogenase 1,Short chain dehydrogenase/reductase family 36C member 1 |
| 2 | C, N (A, B) | (4S)-7-[7-(4,4-difluoropiperidine-1-carbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]-2-methyl[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one | non-polymer | 429.4 | 2 | Chemie (A1CH2) | |||
| 3 | D, O (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | E, F, G, H, P... (A, B) | IODIDE ION | non-polymer | 126.9 | 14 | Chemie (IOD) | |||
| 5 | AA, I, K, M, Z (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | J, L (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | BA, CA (A, B) | water | water | 18.0 | 360 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55509.7 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 4456.9 | |
| All* | Total formula weight | 59966.6 |
