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9PEE

Cryo-EM structure of CCR6 bound by PF-07054894 and OXM2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Human CCR6polymer48054623.01Homo sapiens
2B
(L)
anti-BRIL Fab Light chainpolymer23325343.31Homo sapiens
3C
(K)
anti-BRIL Fab Nanobodypolymer14115755.21synthetic construct
4D
(H)
anti-BRIL Heavy chainpolymer26928832.11Homo sapiens
5E
(A)
N-{[(2R)-4-(bicyclo[1.1.1]pentan-1-yl)-5-oxomorpholin-2-yl]methyl}-1-[4-(trifluoromethyl)phenyl]cyclopropane-1-carboxamidenon-polymer408.41Chemie (A1A1W)
6F
(A)
4-[(2-{[(R)-(1,4-dimethyl-1H-pyrazol-3-yl)(1-methylcyclopentyl)methyl]amino}-3,4-dioxocyclobut-1-en-1-yl)amino]-3-hydroxy-N,N-dimethylpyridine-2-carboxamidenon-polymer466.51Chemie (A1CH1)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight124553.7
Non-Polymers*Number of molecules2
Total formula weight874.9
All*Total formula weight125428.6
*Water molecules are not included.

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PDB entries from 2026-02-18

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