9PC1
Co-crystal structure of the cAMP-dependent protein kinase catalytic subunit alpha with the inhibitor BLU0588
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40657.3 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (house mouse) | PKA C-alpha |
| 2 | B (I) | cAMP-dependent protein kinase inhibitor alpha | polymer | 19 | 2111.3 | 1 | UniProt (P61925) | Homo sapiens | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
| 3 | C (E) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) PubChem (5288834) | |||
| 4 | D (E) | (6M)-N-[(1R,2R)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl]-6-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyridine-3-carboxamide | non-polymer | 423.5 | 1 | Chemie (A1CHQ) | |||
| 5 | E, F (E, I) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42768.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 541.7 | |
| All* | Total formula weight | 43310.3 |
