9P8X
Crystal structure of GITR in complex with ligand-non-competitive Ab#1 Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Ab#1-Fab Heavy Chain | polymer | 225 | 23923.8 | 1 | Homo sapiens | ||
| 2 | B (L) | Ab#1-Fab Light Chain | polymer | 213 | 23124.7 | 1 | Homo sapiens | ||
| 3 | C (A) | Tumor necrosis factor receptor superfamily member 18 | polymer | 130 | 13993.8 | 1 | UniProt (Q9Y5U5) | Homo sapiens (human) | Activation-inducible TNFR family receptor,Glucocorticoid-induced TNFR-related protein |
| 4 | D (H) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F, G (H, L) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 26 - 155 (UniProt: Q9Y5U5)
| PDB | External Database | Details |
|---|---|---|
| Ser 57 | Cys 57 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61042.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 280.3 | |
| All* | Total formula weight | 61322.5 |
