9P8H
In situ human A/P-P/E state 80S ribosome
This is a non-PDB format compatible entry.
Replaces: 9AZNEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AP) | A/P site tRNA | polymer | 142 | 45816.2 | 1 | Homo sapiens (human) | ||
| 2 | B (PE) | P/E site tRNA | polymer | 150 | 48249.5 | 1 | Homo sapiens (human) | ||
| 3 | C (SD) | 40S ribosomal protein S3 | polymer | 454 | 50327.0 | 1 | Homo sapiens (human) | ||
| 4 | D (SF) | 40S ribosomal protein S5 | polymer | 189 | 21327.7 | 1 | UniProt (P46782) | Homo sapiens (human) | Small ribosomal subunit protein uS7 |
| 5 | E (SK) | 40S ribosomal protein S10 | polymer | 98 | 11774.0 | 1 | UniProt (P46783) | Homo sapiens (human) | Small ribosomal subunit protein eS10 |
| 6 | F (SM) | Small ribosomal subunit protein eS12 | polymer | 122 | 13652.0 | 1 | UniProt (P25398) | Homo sapiens (human) | 40S ribosomal protein S12 |
| 7 | G (SP) | 40S ribosomal protein S15 | polymer | 127 | 14931.6 | 1 | UniProt (P62841) | Homo sapiens (human) | RIG protein,Small ribosomal subunit protein uS19 |
| 8 | H (SQ) | Small ribosomal subunit protein uS9 | polymer | 144 | 16249.1 | 1 | UniProt (P62249) | Homo sapiens (human) | 40S ribosomal protein S16 |
| 9 | I (SR) | Small ribosomal subunit protein eS17 | polymer | 135 | 15578.2 | 1 | UniProt (P08708) | Homo sapiens (human) | 40S ribosomal protein S17 |
| 10 | J (SS) | 40S ribosomal protein S18 | polymer | 145 | 17029.8 | 1 | UniProt (P62269) | Homo sapiens (human) | Ke-3,Ke3,Small ribosomal subunit protein uS13 |
| 11 | K (ST) | 40S ribosomal protein S19 | polymer | 143 | 15822.2 | 1 | UniProt (P39019) | Homo sapiens (human) | Small ribosomal subunit protein eS19 |
| 12 | L (SU) | 40S ribosomal protein S20 | polymer | 104 | 11765.9 | 1 | UniProt (P60866) | Homo sapiens (human) | Small ribosomal subunit protein uS10 |
| 13 | M (SZ) | Small ribosomal subunit protein eS25 | polymer | 75 | 8526.1 | 1 | UniProt (P62851) | Homo sapiens (human) | 40S ribosomal protein S25 |
| 14 | N (Sc) | 40S ribosomal protein S28 | polymer | 64 | 7263.4 | 1 | UniProt (P62857) | Homo sapiens (human) | Small ribosomal subunit protein eS28 |
| 15 | O (Sd) | 40S ribosomal protein S29 | polymer | 55 | 6559.6 | 1 | UniProt (P62273) | Homo sapiens (human) | Small ribosomal subunit protein uS14 |
| 16 | P (Sf) | Ubiquitin-40S ribosomal protein S27a | polymer | 67 | 7884.3 | 1 | UniProt (P62979) | Homo sapiens (human) | Ubiquitin carboxyl extension protein 80 |
| 17 | Q (Sg) | Receptor of activated protein C kinase 1 | polymer | 313 | 34669.1 | 1 | UniProt (P63244) | Homo sapiens (human) | Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1 |
| 18 | R (SA) | 40S ribosomal protein SA | polymer | 221 | 24774.4 | 1 | UniProt (P08865) | Homo sapiens (human) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2 |
| 19 | S (SB) | 40S ribosomal protein S3a | polymer | 214 | 24888.3 | 1 | UniProt (P61247) | Homo sapiens (human) | Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1 |
| 20 | T (SC) | 40S ribosomal protein S2 | polymer | 222 | 24587.0 | 1 | UniProt (P15880) | Homo sapiens (human) | 40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5 |
| 21 | U (SE) | Small ribosomal subunit protein eS4, X isoform | polymer | 262 | 29523.7 | 1 | UniProt (P62701) | Homo sapiens (human) | 40S ribosomal protein S4,SCR10,Single copy abundant mRNA protein |
| 22 | V (SG) | 40S ribosomal protein S6 | polymer | 237 | 27471.5 | 1 | UniProt (P62753) | Homo sapiens (human) | Phosphoprotein NP33,Small ribosomal subunit protein eS6 |
| 23 | W (SH) | Small ribosomal subunit protein eS7 | polymer | 186 | 21257.9 | 1 | UniProt (P62081) | Homo sapiens (human) | 40S ribosomal protein S7 |
| 24 | X (SI) | 40S ribosomal protein S8 | polymer | 206 | 24003.0 | 1 | UniProt (P62241) | Homo sapiens (human) | Small ribosomal subunit protein eS8 |
| 25 | Y (SJ) | 40S ribosomal protein S9 | polymer | 185 | 21649.6 | 1 | UniProt (P46781) | Homo sapiens (human) | Small ribosomal subunit protein uS4 |
| 26 | Z (SL) | 40S ribosomal protein S11 | polymer | 153 | 17786.0 | 1 | UniProt (P62280) | Homo sapiens (human) | Small ribosomal subunit protein uS17 |
| 27 | AA (SN) | 40S ribosomal protein S13 | polymer | 150 | 17128.2 | 1 | UniProt (P62277) | Homo sapiens (human) | Small ribosomal subunit protein uS15 |
| 28 | BA (SO) | Small ribosomal subunit protein uS11 | polymer | 140 | 15014.2 | 1 | UniProt (P62263) | Homo sapiens (human) | 40S ribosomal protein S14 |
| 29 | CA (SV) | Small ribosomal subunit protein eS21 | polymer | 83 | 9124.4 | 1 | UniProt (P63220) | Homo sapiens (human) | 40S ribosomal protein S21 |
| 30 | DA (SW) | 40S ribosomal protein S15a | polymer | 129 | 14734.4 | 1 | UniProt (P62244) | Homo sapiens (human) | Small ribosomal subunit protein uS8 |
| 31 | EA (SX) | 40S ribosomal protein S23 | polymer | 141 | 15626.4 | 1 | UniProt (P62266) | Homo sapiens (human) | Small ribosomal subunit protein uS12 |
| 32 | FA (SY) | 40S ribosomal protein S24 | polymer | 131 | 15203.0 | 1 | UniProt (P62847) | Homo sapiens (human) | Small ribosomal subunit protein eS24 |
| 33 | GA (Sa) | 40S ribosomal protein S26 | polymer | 102 | 11742.9 | 1 | UniProt (P62854) | Homo sapiens (human) | Small ribosomal subunit protein eS26 |
| 34 | HA (Sb) | Small ribosomal subunit protein eS27 | polymer | 83 | 9349.0 | 1 | UniProt (P42677) | Homo sapiens (human) | 40S ribosomal protein S27,Metallopan-stimulin 1,MPS-1 |
| 35 | IA (S2) | 18S rRNA | polymer | 1740 | 562093.6 | 1 | Homo sapiens (human) | ||
| 36 | JA (LR) | 60S ribosomal protein L19 | polymer | 187 | 22441.0 | 1 | UniProt (P84098) | Homo sapiens (human) | Large ribosomal subunit protein eL19 |
| 37 | KA (LW) | Ribosomal protein L24 | polymer | 118 | 13761.2 | 1 | UniProt (A0A994J4A5) | Homo sapiens (human) | |
| 38 | LA (CI) | Transcription factor BTF3 | polymer | 31 | 3554.3 | 1 | UniProt (P20290) | Homo sapiens (human) | Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3 |
| 39 | MA (L5) | 28S rRNA | polymer | 3655 | 1185150.6 | 1 | Homo sapiens (human) | ||
| 40 | NA (L7) | 5S rRNA | polymer | 120 | 38691.9 | 1 | GenBank (23898) | Homo sapiens (human) | |
| 41 | OA (L8) | 5.8S rRNA | polymer | 156 | 50157.7 | 1 | GenBank (2795773355) | Homo sapiens (human) | |
| 42 | PA (LA) | 60S ribosomal protein L8 | polymer | 248 | 26998.6 | 1 | UniProt (P62917) | Homo sapiens (human) | Large ribosomal subunit protein uL2 |
| 43 | QA (LB) | Large ribosomal subunit protein uL3 | polymer | 402 | 46079.9 | 1 | UniProt (P39023) | Homo sapiens (human) | |
| 44 | RA (LC) | 60S ribosomal protein L4 | polymer | 368 | 41747.2 | 1 | UniProt (P36578) | Homo sapiens (human) | 60S ribosomal protein L1,Large ribosomal subunit protein uL4 |
| 45 | SA (LD) | Large ribosomal subunit protein uL18 | polymer | 293 | 34008.3 | 1 | UniProt (P46777) | Homo sapiens (human) | |
| 46 | TA (LE) | Large ribosomal subunit protein eL6 | polymer | 250 | 28694.2 | 1 | UniProt (Q02878) | Homo sapiens (human) | 60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107 |
| 47 | UA (LF) | 60S ribosomal protein L7 | polymer | 225 | 26590.7 | 1 | UniProt (P18124) | Homo sapiens (human) | Large ribosomal subunit protein uL30 |
| 48 | VA (LG) | 60S ribosomal protein L7a | polymer | 241 | 27452.5 | 1 | UniProt (P62424) | Homo sapiens (human) | Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3 |
| 49 | WA (LH) | 60S ribosomal protein L9 | polymer | 190 | 21655.3 | 1 | UniProt (P32969) | Homo sapiens (human) | Large ribosomal subunit protein uL6 |
| 50 | XA (LI) | Ribosomal protein uL16-like | polymer | 213 | 24439.8 | 1 | UniProt (Q96L21) | Homo sapiens (human) | 60S ribosomal protein L10-like,Large ribosomal subunit protein uL16-like |
| 51 | YA (LJ) | 60S ribosomal protein L11 | polymer | 176 | 20086.2 | 1 | UniProt (P62913) | Homo sapiens (human) | CLL-associated antigen KW-12,Large ribosomal subunit protein uL5 |
| 52 | ZA (LL) | Large ribosomal subunit protein eL13 | polymer | 210 | 24190.5 | 1 | UniProt (P26373) | Homo sapiens (human) | |
| 53 | AB (LM) | 60S ribosomal protein L14 | polymer | 139 | 16220.3 | 1 | UniProt (P50914) | Homo sapiens (human) | CAG-ISL 7,Large ribosomal subunit protein eL14 |
| 54 | BB (LN) | 60S ribosomal protein L15 | polymer | 203 | 24076.1 | 1 | UniProt (P61313) | Homo sapiens (human) | Large ribosomal subunit protein eL15 |
| 55 | CB (LO) | 60S ribosomal protein L13a | polymer | 201 | 23431.1 | 1 | UniProt (P40429) | Homo sapiens (human) | 23 kDa highly basic protein,Large ribosomal subunit protein uL13 |
| 56 | DB (LP) | 60S ribosomal protein L17 | polymer | 153 | 17757.6 | 1 | UniProt (P18621) | Homo sapiens (human) | 60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1 |
| 57 | EB (LQ) | 60S ribosomal protein L18 | polymer | 187 | 21556.5 | 1 | UniProt (Q07020) | Homo sapiens (human) | Large ribosomal subunit protein eL18 |
| 58 | FB (LS) | 60S ribosomal protein L18a | polymer | 175 | 20677.3 | 1 | UniProt (Q02543) | Homo sapiens (human) | Large ribosomal subunit protein eL20 |
| 59 | GB (LT) | 60S ribosomal protein L21 | polymer | 159 | 18478.8 | 1 | UniProt (P46778) | Homo sapiens (human) | Large ribosomal subunit protein eL21 |
| 60 | HB (LU) | Heparin-binding protein HBp15 | polymer | 101 | 11722.5 | 1 | UniProt (Q7Z4W8) | Homo sapiens (human) | |
| 61 | IB (LV) | 60S ribosomal protein L23 | polymer | 131 | 13972.4 | 1 | UniProt (P62829) | Homo sapiens (human) | 60S ribosomal protein L17,Large ribosomal subunit protein uL14 |
| 62 | JB (LX) | 60S ribosomal protein L23a | polymer | 120 | 13985.5 | 1 | UniProt (P62750) | Homo sapiens (human) | Large ribosomal subunit protein uL23 |
| 63 | KB (LY) | 60S ribosomal protein L26 | polymer | 134 | 15891.8 | 1 | UniProt (P61254) | Homo sapiens (human) | Large ribosomal subunit protein uL24 |
| 64 | LB (LZ) | 60S ribosomal protein L27 | polymer | 135 | 15704.6 | 1 | UniProt (P61353) | Homo sapiens (human) | Large ribosomal subunit protein eL27 |
| 65 | MB (La) | 60S ribosomal protein L27a | polymer | 147 | 16473.3 | 1 | UniProt (P46776) | Homo sapiens (human) | Large ribosomal subunit protein uL15 |
| 66 | NB (Lb) | Large ribosomal subunit protein eL29 | polymer | 109 | 12630.1 | 1 | UniProt (P47914) | Homo sapiens (human) | 60S ribosomal protein L29,Cell surface heparin-binding protein HIP |
| 67 | OB (Lc) | 60S ribosomal protein L30 | polymer | 98 | 10954.9 | 1 | UniProt (P62888) | Homo sapiens (human) | Large ribosomal subunit protein eL30 |
| 68 | PB (Ld) | 60S ribosomal protein L31 | polymer | 107 | 12635.7 | 1 | UniProt (P62899) | Homo sapiens (human) | Large ribosomal subunit protein eL31 |
| 69 | QB (Le) | 60S ribosomal protein L32 | polymer | 128 | 15022.0 | 1 | UniProt (P62910) | Homo sapiens (human) | Large ribosomal subunit protein eL32 |
| 70 | RB (Lf) | 60S ribosomal protein L35a | polymer | 109 | 12433.5 | 1 | UniProt (P18077) | Homo sapiens (human) | Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33 |
| 71 | SB (Lg) | 60S ribosomal protein L34 | polymer | 114 | 12994.6 | 1 | UniProt (P49207) | Homo sapiens (human) | Large ribosomal subunit protein eL34 |
| 72 | TB (Lh) | 60S ribosomal protein L35 | polymer | 122 | 14462.4 | 1 | UniProt (P42766) | Homo sapiens (human) | Large ribosomal subunit protein uL29 |
| 73 | UB (Li) | 60S ribosomal protein L36 | polymer | 102 | 11915.4 | 1 | UniProt (Q9Y3U8) | Homo sapiens (human) | Large ribosomal subunit protein eL36 |
| 74 | VB (Lj) | 60S ribosomal protein L37 | polymer | 86 | 10090.9 | 1 | UniProt (P61927) | Homo sapiens (human) | G1.16,Large ribosomal subunit protein eL37 |
| 75 | WB (Lk) | 60S ribosomal protein L38 | polymer | 69 | 8107.8 | 1 | UniProt (P63173) | Homo sapiens (human) | Large ribosomal subunit protein eL38 |
| 76 | XB (Ll) | 60S ribosomal protein L39 | polymer | 50 | 6295.6 | 1 | UniProt (P62891) | Homo sapiens (human) | Large ribosomal subunit protein eL39 |
| 77 | YB (Lm) | Large ribosomal subunit protein eL40 | polymer | 52 | 6199.6 | 1 | UniProt (P62987) | Homo sapiens (human) | 60S ribosomal protein L40 |
| 78 | ZB (Ln) | 60S ribosomal protein L41 | polymer | 24 | 3344.3 | 1 | UniProt (P62945) | Homo sapiens (human) | HG12,Large ribosomal subunit protein eL41 |
| 79 | AC (Lo) | 60S ribosomal protein L36a | polymer | 105 | 12345.8 | 1 | UniProt (P83881) | Homo sapiens (human) | 60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein,Large ribosomal subunit protein eL42 |
| 80 | BC (Lp) | 60S ribosomal protein L37a | polymer | 91 | 10168.2 | 1 | UniProt (P61513) | Homo sapiens (human) | Large ribosomal subunit protein eL43 |
| 81 | CC (Lr) | 60S ribosomal protein L28 | polymer | 125 | 14320.8 | 1 | UniProt (P46779) | Homo sapiens (human) | Large ribosomal subunit protein eL28 |
| 82 | DC (Ls) | 60S acidic ribosomal protein P0 | polymer | 196 | 21507.0 | 1 | UniProt (P05388) | Homo sapiens (human) | 60S ribosomal protein L10E,Large ribosomal subunit protein uL10 |
| 83 | EC (Lt) | Large ribosomal subunit protein uL11 | polymer | 141 | 15080.4 | 1 | UniProt (P30050) | Homo sapiens (human) | 60S ribosomal protein L12 |
| 84 | FC (CH) | Endothelial differentiation-related factor 1 | polymer | 132 | 14508.5 | 1 | UniProt (O60869) | Homo sapiens (human) | EDF-1,Multiprotein-bridging factor 1,MBF1 |
| 85 | AD, AE, AF, AG, AH... (S2, L5, L8, LA, LB...) | MAGNESIUM ION | non-polymer | 24.3 | 218 | Chemie (MG) | |||
| 86 | IC, IL, JL, KL, LL... (Sa, Lg, Lj, Lm, Lo...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 87 | JJ, NK, OJ, PJ, QK... (L5) | SPERMINE | non-polymer | 202.3 | 7 | Chemie (SPM) | |||
| 88 | EL, IK, JK, KK, LK... (LN, L5, L8) | SPERMIDINE | non-polymer | 145.2 | 10 | Chemie (SPD) |
Sequence modifications
SH: 5 - 193 (UniProt: P62081)
LW: 1 - 124 (UniProt: A0A994J4A5)
Lb: 2 - 122 (UniProt: P47914)
Lt: 7 - 163 (UniProt: P30050)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 108 | deletion |
| - | Arg 109 | deletion |
| - | Thr 110 | deletion |
| PDB | External Database | Details |
|---|---|---|
| - | Ser 64 | deletion |
| - | Glu 65 | deletion |
| - | Glu 66 | deletion |
| - | Ile 67 | deletion |
| - | Gln 68 | deletion |
| - | Lys 69 | deletion |
| PDB | External Database | Details |
|---|---|---|
| - | Lys 77 | deletion |
| - | Pro 78 | deletion |
| - | Lys 79 | deletion |
| - | Glu 80 | deletion |
| - | Val 81 | deletion |
| - | Lys 82 | deletion |
| - | Pro 83 | deletion |
| - | Lys 84 | deletion |
| - | Ile 85 | deletion |
| - | Pro 86 | deletion |
| - | Lys 87 | deletion |
| - | Gly 88 | deletion |
| PDB | External Database | Details |
|---|---|---|
| - | Pro 88 | deletion |
| - | Pro 89 | deletion |
| - | Arg 90 | deletion |
| - | Asp 91 | deletion |
| - | Arg 92 | deletion |
| - | Lys 93 | deletion |
| - | Lys 94 | deletion |
| - | Gln 95 | deletion |
| - | Lys 96 | deletion |
| - | Asn 97 | deletion |
| - | Ile 98 | deletion |
| - | Lys 99 | deletion |
| - | His 100 | deletion |
| - | Ser 101 | deletion |
| - | Gly 102 | deletion |
| - | Asn 103 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 84 |
| Total formula weight | 3324048.6 | |
| Non-Polymers* | Number of molecules | 241 |
| Total formula weight | 8559.8 | |
| All* | Total formula weight | 3332608.4 |
