9P7G
In situ HHT and CHX treated A-P-Z state 80S ribosome
This is a non-PDB format compatible entry.
Replaces: 8UJKEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Zt) | Z site tRNA [Homo sapiens] | polymer | 75 | 24102.3 | 1 | Homo sapiens | ||
| 2 | B (SA) | 40S ribosomal protein SA | polymer | 221 | 24774.4 | 1 | UniProt (P08865) Pfam (PF00318) | Homo sapiens (human) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2 |
| 3 | C (SB) | 40S ribosomal protein S3a | polymer | 214 | 24888.3 | 1 | UniProt (P61247) Pfam (PF01015) | Homo sapiens (human) | Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1 |
| 4 | D (SC) | 40S ribosomal protein S2 | polymer | 222 | 24587.0 | 1 | UniProt (P15880) Pfam (PF00333) Pfam (PF03719) | Homo sapiens (human) | 40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5 |
| 5 | E (SE) | Small ribosomal subunit protein eS4, X isoform | polymer | 262 | 29523.7 | 1 | UniProt (P62701) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Homo sapiens (human) | 40S ribosomal protein S4,SCR10,Single copy abundant mRNA protein |
| 6 | F (SG) | 40S ribosomal protein S6 | polymer | 237 | 27471.5 | 1 | UniProt (P62753) Pfam (PF01092) | Homo sapiens (human) | Phosphoprotein NP33,Small ribosomal subunit protein eS6 |
| 7 | G (SH) | Small ribosomal subunit protein eS7 | polymer | 189 | 21603.2 | 1 | UniProt (P62081) Pfam (PF01251) | Homo sapiens (human) | 40S ribosomal protein S7 |
| 8 | H (SI) | 40S ribosomal protein S8 | polymer | 206 | 24003.0 | 1 | UniProt (P62241) Pfam (PF01201) | Homo sapiens (human) | Small ribosomal subunit protein eS8 |
| 9 | I (SJ) | 40S ribosomal protein S9 | polymer | 185 | 21649.6 | 1 | UniProt (P46781) Pfam (PF00163) Pfam (PF01479) | Homo sapiens (human) | Small ribosomal subunit protein uS4 |
| 10 | J (SL) | 40S ribosomal protein S11 | polymer | 153 | 17786.0 | 1 | UniProt (P62280) Pfam (PF16205) Pfam (PF00366) | Homo sapiens (human) | Small ribosomal subunit protein uS17 |
| 11 | K (SN) | 40S ribosomal protein S13 | polymer | 150 | 17128.2 | 1 | UniProt (P62277) Pfam (PF08069) Pfam (PF00312) | Homo sapiens (human) | Small ribosomal subunit protein uS15 |
| 12 | L (SO) | Small ribosomal subunit protein uS11 | polymer | 140 | 15014.2 | 1 | UniProt (P62263) Pfam (PF00411) | Homo sapiens (human) | 40S ribosomal protein S14 |
| 13 | M (SV) | Small ribosomal subunit protein eS21 | polymer | 83 | 9124.4 | 1 | UniProt (P63220) Pfam (PF01249) | Homo sapiens (human) | 40S ribosomal protein S21 |
| 14 | N (SW) | 40S ribosomal protein S15a | polymer | 129 | 14734.4 | 1 | UniProt (P62244) Pfam (PF00410) | Homo sapiens (human) | Small ribosomal subunit protein uS8 |
| 15 | O (SX) | 40S ribosomal protein S23 | polymer | 141 | 15626.4 | 1 | UniProt (P62266) Pfam (PF00164) | Homo sapiens (human) | Small ribosomal subunit protein uS12 |
| 16 | P (SY) | 40S ribosomal protein S24 | polymer | 131 | 15203.0 | 1 | UniProt (P62847) Pfam (PF01282) | Homo sapiens (human) | Small ribosomal subunit protein eS24 |
| 17 | Q (Sa) | 40S ribosomal protein S26 | polymer | 102 | 11742.9 | 1 | UniProt (P62854) Pfam (PF01283) | Homo sapiens (human) | Small ribosomal subunit protein eS26 |
| 18 | R (Sb) | Small ribosomal subunit protein eS27 | polymer | 83 | 9349.0 | 1 | UniProt (P42677) Pfam (PF01667) | Homo sapiens (human) | 40S ribosomal protein S27,Metallopan-stimulin 1,MPS-1 |
| 19 | S (Se) | Small ribosomal subunit protein eS30 | polymer | 58 | 6539.8 | 1 | UniProt (P62861) Pfam (PF04758) | Homo sapiens (human) | 40S ribosomal protein S30 |
| 20 | T (S2) | 18S rRNA [Homo sapiens] | polymer | 1740 | 562093.6 | 1 | Homo sapiens | ||
| 21 | U (LR) | 60S ribosomal protein L19 | polymer | 187 | 22441.0 | 1 | UniProt (P84098) Pfam (PF01280) Pfam (PF25476) | Homo sapiens (human) | Large ribosomal subunit protein eL19 |
| 22 | V (LW) | Ribosomal protein L24 | polymer | 124 | 14477.0 | 1 | UniProt (A0A994J4A5) Pfam (PF01246) | Homo sapiens (human) | |
| 23 | W (SR) | Small ribosomal subunit protein eS17 | polymer | 135 | 15578.2 | 1 | UniProt (P08708) Pfam (PF00833) | Homo sapiens (human) | 40S ribosomal protein S17 |
| 24 | X (SD) | Small ribosomal subunit protein uS3 | polymer | 227 | 25172.6 | 1 | UniProt (P23396) Pfam (PF07650) Pfam (PF00189) | Homo sapiens (human) | |
| 25 | Y (SF) | 40S ribosomal protein S5 | polymer | 189 | 21327.7 | 1 | UniProt (P46782) Pfam (PF00177) | Homo sapiens (human) | Small ribosomal subunit protein uS7 |
| 26 | Z (SK) | 40S ribosomal protein S10 | polymer | 98 | 11774.0 | 1 | UniProt (P46783) Pfam (PF03501) | Homo sapiens (human) | Small ribosomal subunit protein eS10 |
| 27 | AA (SM) | Small ribosomal subunit protein eS12 | polymer | 122 | 13652.0 | 1 | UniProt (P25398) Pfam (PF01248) | Homo sapiens (human) | 40S ribosomal protein S12 |
| 28 | BA (SP) | Small ribosomal subunit protein uS19 | polymer | 121 | 14092.6 | 1 | UniProt (P62841) Pfam (PF00203) | Homo sapiens (human) | 40S ribosomal protein S15,RIG protein |
| 29 | CA (SQ) | Small ribosomal subunit protein uS9 | polymer | 144 | 16249.1 | 1 | UniProt (P62249) Pfam (PF00380) | Homo sapiens (human) | 40S ribosomal protein S16 |
| 30 | DA (SS) | 40S ribosomal protein S18 | polymer | 145 | 17029.8 | 1 | UniProt (P62269) Pfam (PF00416) | Homo sapiens (human) | Ke-3,Ke3,Small ribosomal subunit protein uS13 |
| 31 | EA (ST) | 40S ribosomal protein S19 | polymer | 143 | 15822.2 | 1 | UniProt (P39019) Pfam (PF01090) | Homo sapiens (human) | Small ribosomal subunit protein eS19 |
| 32 | FA (SU) | 40S ribosomal protein S20 | polymer | 104 | 11765.9 | 1 | UniProt (P60866) Pfam (PF00338) | Homo sapiens (human) | Small ribosomal subunit protein uS10 |
| 33 | GA (SZ) | Small ribosomal subunit protein eS25 | polymer | 75 | 8526.1 | 1 | UniProt (P62851) Pfam (PF03297) | Homo sapiens (human) | 40S ribosomal protein S25 |
| 34 | HA (Sc) | 40S ribosomal protein S28 | polymer | 64 | 7263.4 | 1 | UniProt (P62857) Pfam (PF01200) | Homo sapiens (human) | Small ribosomal subunit protein eS28 |
| 35 | IA (Sd) | 40S ribosomal protein S29 | polymer | 55 | 6559.6 | 1 | UniProt (P62273) Pfam (PF00253) | Homo sapiens (human) | Small ribosomal subunit protein uS14 |
| 36 | JA (Sf) | Ubiquitin-40S ribosomal protein S27a | polymer | 67 | 7884.3 | 1 | UniProt (P62979) Pfam (PF01599) | Homo sapiens (human) | Ubiquitin carboxyl extension protein 80 |
| 37 | KA (Sg) | Receptor of activated protein C kinase 1 | polymer | 313 | 34669.1 | 1 | UniProt (P63244) Pfam (PF00400) | Homo sapiens (human) | Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1 |
| 38 | LA (At) | A site tRNA [Homo sapiens] | polymer | 71 | 22885.6 | 1 | Homo sapiens | ||
| 39 | MA (Pt) | P site tRNA [Homo sapiens] | polymer | 74 | 23825.2 | 1 | Homo sapiens | ||
| 40 | NA (CI) | Transcription factor BTF3 | polymer | 31 | 3554.3 | 1 | UniProt (P20290) | Homo sapiens (human) | Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3 |
| 41 | OA (L5) | 28S rRNA [Homo sapiens] | polymer | 3655 | 1185150.6 | 1 | Homo sapiens | ||
| 42 | PA (L7) | 5S rRNA [Homo sapiens] | polymer | 120 | 38691.9 | 1 | GenBank (23898) | Homo sapiens (human) | |
| 43 | QA (L8) | 5.8S rRNA [Homo sapiens] | polymer | 156 | 50157.7 | 1 | GenBank (2795773355) | Homo sapiens (human) | |
| 44 | RA (LA) | 60S ribosomal protein L8 | polymer | 248 | 26998.6 | 1 | UniProt (P62917) Pfam (PF00181) Pfam (PF03947) | Homo sapiens (human) | Large ribosomal subunit protein uL2 |
| 45 | SA (LB) | Large ribosomal subunit protein uL3 | polymer | 402 | 46079.9 | 1 | UniProt (P39023) Pfam (PF00297) | Homo sapiens (human) | |
| 46 | TA (LC) | 60S ribosomal protein L4 | polymer | 368 | 41747.2 | 1 | UniProt (P36578) Pfam (PF00573) Pfam (PF14374) | Homo sapiens (human) | 60S ribosomal protein L1,Large ribosomal subunit protein uL4 |
| 47 | UA (LD) | Large ribosomal subunit protein uL18 | polymer | 293 | 34008.3 | 1 | UniProt (P46777) Pfam (PF17144) Pfam (PF14204) | Homo sapiens (human) | |
| 48 | VA (LE) | Large ribosomal subunit protein eL6 | polymer | 250 | 28694.2 | 1 | UniProt (Q02878) Pfam (PF03868) Pfam (PF01159) | Homo sapiens (human) | 60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107 |
| 49 | WA (LF) | 60S ribosomal protein L7 | polymer | 225 | 26590.7 | 1 | UniProt (P18124) Pfam (PF08079) Pfam (PF00327) | Homo sapiens (human) | Large ribosomal subunit protein uL30 |
| 50 | XA (LG) | 60S ribosomal protein L7a | polymer | 241 | 27452.5 | 1 | UniProt (P62424) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3 |
| 51 | YA (LH) | 60S ribosomal protein L9 | polymer | 190 | 21655.3 | 1 | UniProt (P32969) Pfam (PF00347) | Homo sapiens (human) | Large ribosomal subunit protein uL6 |
| 52 | ZA (LI) | Ribosomal protein uL16-like | polymer | 213 | 24439.8 | 1 | UniProt (Q96L21) Pfam (PF00252) | Homo sapiens (human) | 60S ribosomal protein L10-like,Large ribosomal subunit protein uL16-like |
| 53 | AB (LJ) | 60S ribosomal protein L11 | polymer | 176 | 20086.2 | 1 | UniProt (P62913) Pfam (PF00281) Pfam (PF00673) | Homo sapiens (human) | CLL-associated antigen KW-12,Large ribosomal subunit protein uL5 |
| 54 | BB (LL) | Large ribosomal subunit protein eL13 | polymer | 210 | 24190.5 | 1 | UniProt (P26373) Pfam (PF01294) | Homo sapiens (human) | |
| 55 | CB (LM) | 60S ribosomal protein L14 | polymer | 139 | 16220.3 | 1 | UniProt (P50914) Pfam (PF01929) | Homo sapiens (human) | CAG-ISL 7,Large ribosomal subunit protein eL14 |
| 56 | DB (LN) | 60S ribosomal protein L15 | polymer | 203 | 24076.1 | 1 | UniProt (P61313) Pfam (PF00827) | Homo sapiens (human) | Large ribosomal subunit protein eL15 |
| 57 | EB (LO) | 60S ribosomal protein L13a | polymer | 201 | 23431.1 | 1 | UniProt (P40429) Pfam (PF00572) | Homo sapiens (human) | 23 kDa highly basic protein,Large ribosomal subunit protein uL13 |
| 58 | FB (LP) | 60S ribosomal protein L17 | polymer | 153 | 17757.6 | 1 | UniProt (P18621) Pfam (PF00237) | Homo sapiens (human) | 60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1 |
| 59 | GB (LQ) | 60S ribosomal protein L18 | polymer | 187 | 21556.5 | 1 | UniProt (Q07020) Pfam (PF17135) | Homo sapiens (human) | Large ribosomal subunit protein eL18 |
| 60 | HB (LS) | 60S ribosomal protein L18a | polymer | 175 | 20677.3 | 1 | UniProt (Q02543) Pfam (PF01775) | Homo sapiens (human) | Large ribosomal subunit protein eL20 |
| 61 | IB (LT) | 60S ribosomal protein L21 | polymer | 159 | 18478.8 | 1 | UniProt (P46778) Pfam (PF01157) | Homo sapiens (human) | Large ribosomal subunit protein eL21 |
| 62 | JB (LU) | Heparin-binding protein HBp15 | polymer | 101 | 11722.5 | 1 | UniProt (Q7Z4W8) | Homo sapiens (human) | |
| 63 | KB (LV) | 60S ribosomal protein L23 | polymer | 131 | 13972.4 | 1 | UniProt (P62829) Pfam (PF00238) | Homo sapiens (human) | 60S ribosomal protein L17,Large ribosomal subunit protein uL14 |
| 64 | LB (LX) | 60S ribosomal protein L23a | polymer | 120 | 13985.5 | 1 | UniProt (P62750) Pfam (PF03939) Pfam (PF00276) | Homo sapiens (human) | Large ribosomal subunit protein uL23 |
| 65 | MB (LY) | 60S ribosomal protein L26 | polymer | 134 | 15891.8 | 1 | UniProt (P61254) Pfam (PF16906) Pfam (PF00467) | Homo sapiens (human) | Large ribosomal subunit protein uL24 |
| 66 | NB (LZ) | 60S ribosomal protein L27 | polymer | 135 | 15704.6 | 1 | UniProt (P61353) Pfam (PF00467) Pfam (PF01777) | Homo sapiens (human) | Large ribosomal subunit protein eL27 |
| 67 | OB (La) | 60S ribosomal protein L27a | polymer | 147 | 16473.3 | 1 | UniProt (P46776) Pfam (PF00828) | Homo sapiens (human) | Large ribosomal subunit protein uL15 |
| 68 | PB (Lb) | Large ribosomal subunit protein eL29 | polymer | 121 | 13965.8 | 1 | UniProt (P47914) Pfam (PF01779) | Homo sapiens (human) | 60S ribosomal protein L29,Cell surface heparin-binding protein HIP |
| 69 | QB (Lc) | 60S ribosomal protein L30 | polymer | 98 | 10954.9 | 1 | UniProt (P62888) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL30 |
| 70 | RB (Ld) | 60S ribosomal protein L31 | polymer | 107 | 12635.7 | 1 | UniProt (P62899) Pfam (PF01198) | Homo sapiens (human) | Large ribosomal subunit protein eL31 |
| 71 | SB (Le) | 60S ribosomal protein L32 | polymer | 128 | 15022.0 | 1 | UniProt (P62910) Pfam (PF01655) | Homo sapiens (human) | Large ribosomal subunit protein eL32 |
| 72 | TB (Lf) | 60S ribosomal protein L35a | polymer | 109 | 12433.5 | 1 | UniProt (P18077) Pfam (PF01247) | Homo sapiens (human) | Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33 |
| 73 | UB (Lg) | 60S ribosomal protein L34 | polymer | 114 | 12994.6 | 1 | UniProt (P49207) Pfam (PF01199) | Homo sapiens (human) | Large ribosomal subunit protein eL34 |
| 74 | VB (Lh) | 60S ribosomal protein L35 | polymer | 122 | 14462.4 | 1 | UniProt (P42766) Pfam (PF00831) | Homo sapiens (human) | Large ribosomal subunit protein uL29 |
| 75 | WB (Li) | 60S ribosomal protein L36 | polymer | 102 | 11915.4 | 1 | UniProt (Q9Y3U8) Pfam (PF01158) | Homo sapiens (human) | Large ribosomal subunit protein eL36 |
| 76 | XB (Lj) | 60S ribosomal protein L37 | polymer | 86 | 10090.9 | 1 | UniProt (P61927) Pfam (PF01907) | Homo sapiens (human) | G1.16,Large ribosomal subunit protein eL37 |
| 77 | YB (Lk) | 60S ribosomal protein L38 | polymer | 69 | 8107.8 | 1 | UniProt (P63173) Pfam (PF01781) | Homo sapiens (human) | Large ribosomal subunit protein eL38 |
| 78 | ZB (Ll) | 60S ribosomal protein L39 | polymer | 50 | 6295.6 | 1 | UniProt (P62891) Pfam (PF00832) | Homo sapiens (human) | Large ribosomal subunit protein eL39 |
| 79 | AC (Lm) | Large ribosomal subunit protein eL40 | polymer | 52 | 6199.6 | 1 | UniProt (P62987) Pfam (PF01020) | Homo sapiens (human) | 60S ribosomal protein L40 |
| 80 | BC (Ln) | 60S ribosomal protein L41 | polymer | 24 | 3344.3 | 1 | UniProt (P62945) Pfam (PF05162) | Homo sapiens (human) | HG12,Large ribosomal subunit protein eL41 |
| 81 | CC (Lo) | 60S ribosomal protein L36a | polymer | 105 | 12345.8 | 1 | UniProt (P83881) Pfam (PF00935) | Homo sapiens (human) | 60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein,Large ribosomal subunit protein eL42 |
| 82 | DC (Lp) | 60S ribosomal protein L37a | polymer | 91 | 10168.2 | 1 | UniProt (P61513) Pfam (PF01780) | Homo sapiens (human) | Large ribosomal subunit protein eL43 |
| 83 | EC (Lr) | 60S ribosomal protein L28 | polymer | 125 | 14320.8 | 1 | UniProt (P46779) Pfam (PF01778) | Homo sapiens (human) | Large ribosomal subunit protein eL28 |
| 84 | FC (Ls) | 60S acidic ribosomal protein P0 | polymer | 196 | 21507.0 | 1 | UniProt (P05388) Pfam (PF00466) Pfam (PF17777) | Homo sapiens (human) | 60S ribosomal protein L10E,Large ribosomal subunit protein uL10 |
| 85 | GC (Lt) | Large ribosomal subunit protein uL11 | polymer | 157 | 16972.6 | 1 | UniProt (P30050) Pfam (PF03946) Pfam (PF00298) | Homo sapiens (human) | 60S ribosomal protein L12 |
| 86 | AD, AE, AF, AG, AH... (S2, L5, L7, L8, LA...) | MAGNESIUM ION | non-polymer | 24.3 | 219 | Chemie (MG) PubChem (888) | |||
| 87 | IC, ML, NL, OL, PL... (Sa, Lg, Lj, Lm, Lo...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 88 | JJ, NK, OJ, PJ, QK... (L5) | SPERMINE | non-polymer | 202.3 | 7 | Chemie (SPM) PubChem (1103) | |||
| 89 | BL, IK, JK, KK, LK... (L8, L5) | SPERMIDINE | non-polymer | 145.2 | 10 | Chemie (SPD) PubChem (1102) | |||
| 90 | TK (L5) | 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione | non-polymer | 281.3 | 1 | Chemie (3HE) | |||
| 91 | UK (L5) | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine | non-polymer | 545.6 | 1 | Chemie (HMT) PubChem (3628) PubChem (285033) PubChem (45356872) PubChem (71211769) PubChem (53298607) PubChem (58786313) PubChem (60128438) PubChem (56841046) PubChem (68337922) PubChem (60128444) PubChem (70826802) PubChem (70826803) PubChem (71296925) PubChem (5458297) PubChem (72332) PubChem (6604865) PubChem (90392075) PubChem (10951700) PubChem (92850103) PubChem (92850104) PubChem (93956055) PubChem (93956056) PubChem (93956058) PubChem (14368099) PubChem (14368100) PubChem (93956057) PubChem (118911842) PubChem (138107280) PubChem (140440283) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 85 |
| Total formula weight | 3271122.8 | |
| Non-Polymers* | Number of molecules | 244 |
| Total formula weight | 9411.1 | |
| All* | Total formula weight | 3280533.9 |
