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9P7G

In situ HHT and CHX treated A-P-Z state 80S ribosome

This is a non-PDB format compatible entry.
Replaces:  8UJK
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Zt)
Z site tRNA [Homo sapiens]polymer7524102.31Homo sapiens
2B
(SA)
40S ribosomal protein SApolymer22124774.41UniProt (P08865)Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
3C
(SB)
40S ribosomal protein S3apolymer21424888.31UniProt (P61247)Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
4D
(SC)
40S ribosomal protein S2polymer22224587.01UniProt (P15880)Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
5E
(SE)
Small ribosomal subunit protein eS4, X isoformpolymer26229523.71UniProt (P62701)Homo sapiens (human)40S ribosomal protein S4,SCR10,Single copy abundant mRNA protein
6F
(SG)
40S ribosomal protein S6polymer23727471.51UniProt (P62753)Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
7G
(SH)
Small ribosomal subunit protein eS7polymer18921603.21UniProt (P62081)Homo sapiens (human)40S ribosomal protein S7
8H
(SI)
40S ribosomal protein S8polymer20624003.01UniProt (P62241)Homo sapiens (human)Small ribosomal subunit protein eS8
9I
(SJ)
40S ribosomal protein S9polymer18521649.61UniProt (P46781)Homo sapiens (human)Small ribosomal subunit protein uS4
10J
(SL)
40S ribosomal protein S11polymer15317786.01UniProt (P62280)Homo sapiens (human)Small ribosomal subunit protein uS17
11K
(SN)
40S ribosomal protein S13polymer15017128.21UniProt (P62277)Homo sapiens (human)Small ribosomal subunit protein uS15
12L
(SO)
Small ribosomal subunit protein uS11polymer14015014.21UniProt (P62263)Homo sapiens (human)40S ribosomal protein S14
13M
(SV)
Small ribosomal subunit protein eS21polymer839124.41UniProt (P63220)Homo sapiens (human)40S ribosomal protein S21
14N
(SW)
40S ribosomal protein S15apolymer12914734.41UniProt (P62244)Homo sapiens (human)Small ribosomal subunit protein uS8
15O
(SX)
40S ribosomal protein S23polymer14115626.41UniProt (P62266)Homo sapiens (human)Small ribosomal subunit protein uS12
16P
(SY)
40S ribosomal protein S24polymer13115203.01UniProt (P62847)Homo sapiens (human)Small ribosomal subunit protein eS24
17Q
(Sa)
40S ribosomal protein S26polymer10211742.91UniProt (P62854)Homo sapiens (human)Small ribosomal subunit protein eS26
18R
(Sb)
Small ribosomal subunit protein eS27polymer839349.01UniProt (P42677)Homo sapiens (human)40S ribosomal protein S27,Metallopan-stimulin 1,MPS-1
19S
(Se)
Small ribosomal subunit protein eS30polymer586539.81UniProt (P62861)Homo sapiens (human)40S ribosomal protein S30
20T
(S2)
18S rRNA [Homo sapiens]polymer1740562093.61Homo sapiens
21U
(LR)
60S ribosomal protein L19polymer18722441.01UniProt (P84098)Homo sapiens (human)Large ribosomal subunit protein eL19
22V
(LW)
Ribosomal protein L24polymer12414477.01UniProt (A0A994J4A5)Homo sapiens (human)
23W
(SR)
Small ribosomal subunit protein eS17polymer13515578.21UniProt (P08708)Homo sapiens (human)40S ribosomal protein S17
24X
(SD)
Small ribosomal subunit protein uS3polymer22725172.61UniProt (P23396)Homo sapiens (human)
25Y
(SF)
40S ribosomal protein S5polymer18921327.71UniProt (P46782)Homo sapiens (human)Small ribosomal subunit protein uS7
26Z
(SK)
40S ribosomal protein S10polymer9811774.01UniProt (P46783)Homo sapiens (human)Small ribosomal subunit protein eS10
27AA
(SM)
Small ribosomal subunit protein eS12polymer12213652.01UniProt (P25398)Homo sapiens (human)40S ribosomal protein S12
28BA
(SP)
Small ribosomal subunit protein uS19polymer12114092.61UniProt (P62841)Homo sapiens (human)40S ribosomal protein S15,RIG protein
29CA
(SQ)
Small ribosomal subunit protein uS9polymer14416249.11UniProt (P62249)Homo sapiens (human)40S ribosomal protein S16
30DA
(SS)
40S ribosomal protein S18polymer14517029.81UniProt (P62269)Homo sapiens (human)Ke-3,Ke3,Small ribosomal subunit protein uS13
31EA
(ST)
40S ribosomal protein S19polymer14315822.21UniProt (P39019)Homo sapiens (human)Small ribosomal subunit protein eS19
32FA
(SU)
40S ribosomal protein S20polymer10411765.91UniProt (P60866)Homo sapiens (human)Small ribosomal subunit protein uS10
33GA
(SZ)
Small ribosomal subunit protein eS25polymer758526.11UniProt (P62851)Homo sapiens (human)40S ribosomal protein S25
34HA
(Sc)
40S ribosomal protein S28polymer647263.41UniProt (P62857)Homo sapiens (human)Small ribosomal subunit protein eS28
35IA
(Sd)
40S ribosomal protein S29polymer556559.61UniProt (P62273)Homo sapiens (human)Small ribosomal subunit protein uS14
36JA
(Sf)
Ubiquitin-40S ribosomal protein S27apolymer677884.31UniProt (P62979)Homo sapiens (human)Ubiquitin carboxyl extension protein 80
37KA
(Sg)
Receptor of activated protein C kinase 1polymer31334669.11UniProt (P63244)Homo sapiens (human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
38LA
(At)
A site tRNA [Homo sapiens]polymer7122885.61Homo sapiens
39MA
(Pt)
P site tRNA [Homo sapiens]polymer7423825.21Homo sapiens
40NA
(CI)
Transcription factor BTF3polymer313554.31UniProt (P20290)Homo sapiens (human)Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3
41OA
(L5)
28S rRNA [Homo sapiens]polymer36551185150.61Homo sapiens
42PA
(L7)
5S rRNA [Homo sapiens]polymer12038691.91GenBank (23898)Homo sapiens (human)
43QA
(L8)
5.8S rRNA [Homo sapiens]polymer15650157.71GenBank (2795773355)Homo sapiens (human)
44RA
(LA)
60S ribosomal protein L8polymer24826998.61UniProt (P62917)Homo sapiens (human)Large ribosomal subunit protein uL2
45SA
(LB)
Large ribosomal subunit protein uL3polymer40246079.91UniProt (P39023)Homo sapiens (human)
46TA
(LC)
60S ribosomal protein L4polymer36841747.21UniProt (P36578)Homo sapiens (human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
47UA
(LD)
Large ribosomal subunit protein uL18polymer29334008.31UniProt (P46777)Homo sapiens (human)
48VA
(LE)
Large ribosomal subunit protein eL6polymer25028694.21UniProt (Q02878)Homo sapiens (human)60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
49WA
(LF)
60S ribosomal protein L7polymer22526590.71UniProt (P18124)Homo sapiens (human)Large ribosomal subunit protein uL30
50XA
(LG)
60S ribosomal protein L7apolymer24127452.51UniProt (P62424)Homo sapiens (human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
51YA
(LH)
60S ribosomal protein L9polymer19021655.31UniProt (P32969)Homo sapiens (human)Large ribosomal subunit protein uL6
52ZA
(LI)
Ribosomal protein uL16-likepolymer21324439.81UniProt (Q96L21)Homo sapiens (human)60S ribosomal protein L10-like,Large ribosomal subunit protein uL16-like
53AB
(LJ)
60S ribosomal protein L11polymer17620086.21UniProt (P62913)Homo sapiens (human)CLL-associated antigen KW-12,Large ribosomal subunit protein uL5
54BB
(LL)
Large ribosomal subunit protein eL13polymer21024190.51UniProt (P26373)Homo sapiens (human)
55CB
(LM)
60S ribosomal protein L14polymer13916220.31UniProt (P50914)Homo sapiens (human)CAG-ISL 7,Large ribosomal subunit protein eL14
56DB
(LN)
60S ribosomal protein L15polymer20324076.11UniProt (P61313)Homo sapiens (human)Large ribosomal subunit protein eL15
57EB
(LO)
60S ribosomal protein L13apolymer20123431.11UniProt (P40429)Homo sapiens (human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
58FB
(LP)
60S ribosomal protein L17polymer15317757.61UniProt (P18621)Homo sapiens (human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
59GB
(LQ)
60S ribosomal protein L18polymer18721556.51UniProt (Q07020)Homo sapiens (human)Large ribosomal subunit protein eL18
60HB
(LS)
60S ribosomal protein L18apolymer17520677.31UniProt (Q02543)Homo sapiens (human)Large ribosomal subunit protein eL20
61IB
(LT)
60S ribosomal protein L21polymer15918478.81UniProt (P46778)Homo sapiens (human)Large ribosomal subunit protein eL21
62JB
(LU)
Heparin-binding protein HBp15polymer10111722.51UniProt (Q7Z4W8)Homo sapiens (human)
63KB
(LV)
60S ribosomal protein L23polymer13113972.41UniProt (P62829)Homo sapiens (human)60S ribosomal protein L17,Large ribosomal subunit protein uL14
64LB
(LX)
60S ribosomal protein L23apolymer12013985.51UniProt (P62750)Homo sapiens (human)Large ribosomal subunit protein uL23
65MB
(LY)
60S ribosomal protein L26polymer13415891.81UniProt (P61254)Homo sapiens (human)Large ribosomal subunit protein uL24
66NB
(LZ)
60S ribosomal protein L27polymer13515704.61UniProt (P61353)Homo sapiens (human)Large ribosomal subunit protein eL27
67OB
(La)
60S ribosomal protein L27apolymer14716473.31UniProt (P46776)Homo sapiens (human)Large ribosomal subunit protein uL15
68PB
(Lb)
Large ribosomal subunit protein eL29polymer12113965.81UniProt (P47914)Homo sapiens (human)60S ribosomal protein L29,Cell surface heparin-binding protein HIP
69QB
(Lc)
60S ribosomal protein L30polymer9810954.91UniProt (P62888)Homo sapiens (human)Large ribosomal subunit protein eL30
70RB
(Ld)
60S ribosomal protein L31polymer10712635.71UniProt (P62899)Homo sapiens (human)Large ribosomal subunit protein eL31
71SB
(Le)
60S ribosomal protein L32polymer12815022.01UniProt (P62910)Homo sapiens (human)Large ribosomal subunit protein eL32
72TB
(Lf)
60S ribosomal protein L35apolymer10912433.51UniProt (P18077)Homo sapiens (human)Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33
73UB
(Lg)
60S ribosomal protein L34polymer11412994.61UniProt (P49207)Homo sapiens (human)Large ribosomal subunit protein eL34
74VB
(Lh)
60S ribosomal protein L35polymer12214462.41UniProt (P42766)Homo sapiens (human)Large ribosomal subunit protein uL29
75WB
(Li)
60S ribosomal protein L36polymer10211915.41UniProt (Q9Y3U8)Homo sapiens (human)Large ribosomal subunit protein eL36
76XB
(Lj)
60S ribosomal protein L37polymer8610090.91UniProt (P61927)Homo sapiens (human)G1.16,Large ribosomal subunit protein eL37
77YB
(Lk)
60S ribosomal protein L38polymer698107.81UniProt (P63173)Homo sapiens (human)Large ribosomal subunit protein eL38
78ZB
(Ll)
60S ribosomal protein L39polymer506295.61UniProt (P62891)Homo sapiens (human)Large ribosomal subunit protein eL39
79AC
(Lm)
Large ribosomal subunit protein eL40polymer526199.61UniProt (P62987)Homo sapiens (human)60S ribosomal protein L40
80BC
(Ln)
60S ribosomal protein L41polymer243344.31UniProt (P62945)Homo sapiens (human)HG12,Large ribosomal subunit protein eL41
81CC
(Lo)
60S ribosomal protein L36apolymer10512345.81UniProt (P83881)Homo sapiens (human)60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein,Large ribosomal subunit protein eL42
82DC
(Lp)
60S ribosomal protein L37apolymer9110168.21UniProt (P61513)Homo sapiens (human)Large ribosomal subunit protein eL43
83EC
(Lr)
60S ribosomal protein L28polymer12514320.81UniProt (P46779)Homo sapiens (human)Large ribosomal subunit protein eL28
84FC
(Ls)
60S acidic ribosomal protein P0polymer19621507.01UniProt (P05388)Homo sapiens (human)60S ribosomal protein L10E,Large ribosomal subunit protein uL10
85GC
(Lt)
Large ribosomal subunit protein uL11polymer15716972.61UniProt (P30050)Homo sapiens (human)60S ribosomal protein L12
86AD, AE, AF, AG, AH...
(S2, L5, L7, L8, LA...)
MAGNESIUM IONnon-polymer24.3219Chemie (MG)
87IC, ML, NL, OL, PL...
(Sa, Lg, Lj, Lm, Lo...)
ZINC IONnon-polymer65.46Chemie (ZN)
88JJ, NK, OJ, PJ, QK...
(L5)
SPERMINEnon-polymer202.37Chemie (SPM)
89BL, IK, JK, KK, LK...
(L8, L5)
SPERMIDINEnon-polymer145.210Chemie (SPD)
90TK
(L5)
4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dionenon-polymer281.31Chemie (3HE)
91UK
(L5)
(3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxinenon-polymer545.61Chemie (HMT)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains85
Total formula weight3271122.8
Non-Polymers*Number of molecules244
Total formula weight9411.1
All*Total formula weight3280533.9
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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