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9P4Z

Human EAAT3 with sodium bound at inward facing state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Excitatory amino acid transporter 3polymer52657275.21UniProt (P43005)Homo sapiens (human)Excitatory amino-acid carrier 1,Neuronal and epithelial glutamate transporter,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 member 1
2B, C
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
3D
(A)
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.81Chemie (9Z9)
4E
(A)
CHOLESTEROLnon-polymer386.71Chemie (CLR)
Sequence modifications
A: 1 - 524 (UniProt: P43005)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Thr 178Asn 178engineered mutation
Thr 195Asn 195engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57275.2
Non-Polymers*Number of molecules4
Total formula weight977.4
All*Total formula weight58252.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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