9P4Y
Human EAAT3 with compound 3e and digitonin.glyco-diosgenin bound at inward facing state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Excitatory amino acid transporter 3 | polymer | 526 | 57275.2 | 1 | UniProt (P43005) Pfam (PF00375) | Homo sapiens (human) | Excitatory amino-acid carrier 1,Neuronal and epithelial glutamate transporter,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 member 1 |
| 2 | B (A) | (4R)-8-bromo-2-(furan-2-yl)-N-(2-methylphenyl)imidazo[1,2-a]pyridin-3-amine | non-polymer | 368.2 | 1 | Chemie (A1CG9) | |||
| 3 | C (A) | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 1 | Chemie (9Z9) | |||
| 4 | D, E (A) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
| 5 | F (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 524 (UniProt: P43005)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Thr 178 | Asn 178 | engineered mutation |
| Thr 195 | Asn 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57275.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1686.3 | |
| All* | Total formula weight | 58961.5 |
