9P4F

Cryo-EM structure of Nectin-2 complex with Fab F1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Nectin-2	polymer	363	38683.9	2	UniProt (Q92692) Pfam (PF07686) Pfam (PF08205)	Homo sapiens (human)	Herpes virus entry mediator B,Herpesvirus entry mediator B,HveB,Nectin cell adhesion molecule 2,Poliovirus receptor-related protein 2
2	B, E (B, E)	F1 light chain	polymer	217	23602.1	2		Homo sapiens (human)
3	C, F (C, F)	F1 heavy chain	polymer	229	24291.0	2		Homo sapiens (human)

Sequence modifications

A, D: 1 - 330 (UniProt: Q92692)

PDB	External Database	Details
Ser 331	-	expression tag
Arg 332	-	expression tag
Gly 333	-	expression tag
Ser 334	-	expression tag
Ala 335	-	expression tag
Trp 336	-	expression tag
Ser 337	-	expression tag
His 338	-	expression tag
Pro 339	-	expression tag
Gln 340	-	expression tag
Phe 341	-	expression tag
Glu 342	-	expression tag
Lys 343	-	expression tag
Gly 344	-	expression tag
Gly 345	-	expression tag
Gly 346	-	expression tag
Ser 347	-	expression tag
Gly 348	-	expression tag
Gly 349	-	expression tag
Gly 350	-	expression tag
Ser 351	-	expression tag
Gly 352	-	expression tag
Gly 353	-	expression tag
Ser 354	-	expression tag
Ala 355	-	expression tag
Trp 356	-	expression tag
Ser 357	-	expression tag
His 358	-	expression tag
Pro 359	-	expression tag
Gln 360	-	expression tag
Phe 361	-	expression tag
Glu 362	-	expression tag
Lys 363	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	173154.3
All*	Total formula weight	173154.3

*Water molecules are not included.