9P33
Crystal structure of the Bromo domain 1 in human Bromodomain Containing Protein 4 with a compound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | (3R,4R)-4-{(5M)-5-{2-[2-methyl-5-(propan-2-yl)phenoxy]pyrimidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}pyrrolidin-3-ol | non-polymer | 523.5 | 1 | Chemie (A1CGX) | |||
| 4 | D (A) | (3S,4R)-4-{(5M)-5-{2-[2-methyl-5-(propan-2-yl)phenoxy]pyrimidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}pyrrolidin-3-ol | non-polymer | 523.5 | 1 | Chemie (A1C7U) | |||
| 5 | E (A) | (3S,4S)-4-{(5M)-5-{2-[2-methyl-5-(propan-2-yl)phenoxy]pyrimidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}pyrrolidin-3-ol | non-polymer | 523.5 | 1 | Chemie (A1C7T) | |||
| 6 | F (A) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15099.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1632.7 | |
| All* | Total formula weight | 16732.1 |
