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9P2R

Extended, CYR715-bound state of Manduca sexta soluble guanylate cyclase mutant beta C122S

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Soluble guanylyl cyclase alpha-1 subunitpolymer69978598.71UniProt (O77105)
Pfam (PF07700)
Pfam (PF07701)
Pfam (PF00211)
Manduca sexta (tobacco hornworm)
2B
(B)
Guanylate cyclase soluble subunit beta-1polymer60068165.91UniProt (O77106)
Pfam (PF07700)
Pfam (PF07701)
Pfam (PF00211)
Manduca sexta (tobacco hornworm)Guanylate cyclase soluble subunit beta-3,Soluble guanylate cyclase small subunit
3C
(A)
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERnon-polymer521.21Chemie (G2P)
4D
(B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
5E
(B)
(2S,3R)-1-{5-fluoro-2-[(5P)-1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl]pyrimidin-4-yl}-3-methylpiperidine-2-carboxylic acidnon-polymer480.51Chemie (A1CGK)
Sequence modifications
B: 1 - 600 (UniProt: O77106)
PDBExternal DatabaseDetails
Ser 122Cys 122engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight146764.7
Non-Polymers*Number of molecules3
Total formula weight1618.2
All*Total formula weight148382.8
*Water molecules are not included.

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PDB entries from 2026-01-14

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