9P1H

100K human S-adenosylmethionine decarboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	S-adenosylmethionine decarboxylase alpha chain	polymer	267	30686.0	2	UniProt (P17707) Pfam (PF01536)	Homo sapiens (human)
2	B, C (B, D)	S-adenosylmethionine decarboxylase beta chain	polymer	80	9375.4	2	UniProt (P17707)	Homo sapiens (human)
3	E, I (A, C)	1,4-DIAMINOBUTANE	non-polymer		88.2	2	Chemie (PUT)
4	F, J (A, C)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
5	G, H, K (A, C)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6	L, M, N, O (A, B, D, C)	water	water		18.0	362	Chemie (HOH)

Sequence modifications

A, C: 68 - 334 (UniProt: P17707)

PDB	External Database	Details
Pyr 68	Ser 68	modified residue

B, D: 2 - 67 (UniProt: P17707)

PDB	External Database	Details
Met -12	-	initiating methionine
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80122.7
Non-Polymers*	Number of molecules	7
	Total formula weight	696.9
All*	Total formula weight	80819.6

*Water molecules are not included.