9P0P
Crystal structure of 23S rRNA methyltransferase Cfr, apoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribosomal RNA large subunit methyltransferase Cfr | polymer | 349 | 39911.6 | 1 | UniProt (A5HBL2) | Staphylococcus aureus | 23S rRNA (adenine(2503)-C(8))-methyltransferase,23S rRNA m8A2503 methyltransferase |
| 2 | B (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: A5HBL2)
| PDB | External Database | Details |
|---|---|---|
| Lys 2 | Asn 2 | engineered mutation |
| Gly 4 | Asn 4 | engineered mutation |
| Trp 15 | Phe 15 | engineered mutation |
| Met 26 | Ile 26 | engineered mutation |
| Thr 39 | Ser 39 | engineered mutation |
| Thr 45 | Lys 45 | engineered mutation |
| Asn 46 | Val 46 | engineered mutation |
| Gln 50 | Leu 50 | engineered mutation |
| Ile 68 | Leu 68 | engineered mutation |
| Asp 86 | Lys 86 | engineered mutation |
| Gly 87 | Asn 87 | engineered mutation |
| Ile 94 | Asn 94 | engineered mutation |
| Val 172 | Ser 172 | engineered mutation |
| Leu 200 | Ile 200 | engineered mutation |
| Tyr 243 | His 243 | engineered mutation |
| Lys 246 | Leu 246 | engineered mutation |
| Lys 269 | Asn 269 | engineered mutation |
| Asn 323 | His 323 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39911.6 | |
| All* | Total formula weight | 39911.6 |
