9OZX

Crystal structure of ZNRF3 RING in complex with UbcH5b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase ZNRF3	polymer	97	11042.6	1	UniProt (Q9ULT6) Pfam (PF17123)	Homo sapiens (human)	RING finger protein 203,RING-type E3 ubiquitin transferase ZNRF3,Zinc/RING finger protein 3
2	B (B)	Ubiquitin-conjugating enzyme E2 D2	polymer	151	17094.6	1	UniProt (P62837) Pfam (PF00179)	Homo sapiens (human)	(E3-independent) E2 ubiquitin-conjugating enzyme D2,E2 ubiquitin-conjugating enzyme D2,Ubiquitin carrier protein D2,Ubiquitin-conjugating enzyme E2(17)KB 2,Ubiquitin-conjugating enzyme E2-17 kDa 2,Ubiquitin-protein ligase D2,p53-regulated ubiquitin-conjugating enzyme 1
3	C, D (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)

Sequence modifications

A: 249 - 341 (UniProt: Q9ULT6)

PDB	External Database	Details
Gln 245	-	expression tag
Gly 246	-	expression tag
Pro 247	-	expression tag
Gly 248	-	expression tag

B: 1 - 147 (UniProt: P62837)

PDB	External Database	Details
Gln -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28137.2
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	28268.0

*Water molecules are not included.