9OXS
CRYO-EM STRUCTURE OF the human mPSF IN COMPLEX WITH THE AAUAAU poly(A) signal
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cleavage and polyadenylation specificity factor subunit 1 | polymer | 1443 | 161074.2 | 1 | UniProt (Q10570) Pfam (PF10433) Pfam (PF23726) Pfam (PF03178) | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit |
| 2 | B (B) | pre-mRNA 3' end processing protein WDR33 | polymer | 574 | 66053.1 | 1 | UniProt (Q9C0J8) Pfam (PF00400) | Homo sapiens (human) | WD repeat-containing protein 33,WD repeat-containing protein of 146 kDa |
| 3 | C (C) | Isoform 2 of Cleavage and polyadenylation specificity factor subunit 4 | polymer | 244 | 27589.0 | 1 | UniProt (O95639) Pfam (PF15663) Pfam (PF00642) Pfam (PF00098) | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 30 kDa subunit,CPSF 30 kDa subunit,NS1 effector domain-binding protein 1,Neb-1,No arches homolog |
| 4 | D (E) | RNA (5'-R(P*AP*AP*UP*AP*AP*UP*C)-3') | polymer | 12 | 3804.3 | 1 | Homo sapiens | ||
| 5 | E, F, G (C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
B: 2 - 572 (UniProt: Q9C0J8)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258520.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 258716.9 |
