9OWE

CryoEM structure of stabilized dengue 3 virus envelope glycoprotein in complex with Fab of F25.S02

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Genome polyprotein	polymer	406	45001.3	2	UniProt (Q07019)	dengue virus type 3
2	C, E (C, H)	F25.S02 Heavy chain	polymer	238	25575.7	2		Homo sapiens
3	D, F (D, L)	F25.S02 Light chain	polymer	217	23023.5	2		Homo sapiens
4	G, H (E, F)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	I, J (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B: 1 - 397 (UniProt: Q07019)

PDB	External Database	Details
Lys 29	Gly 195	conflict
Val 33	Thr 199	conflict
Met 35	Ala 201	conflict
Asp 106	Gly 272	conflict
Cys 257	Ala 423	conflict
Trp 277	Phe 443	conflict
Pro 278	Ala 444	conflict
Gly 396	Ile 562	conflict
Ser 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	187201.0
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	188816.5

*Water molecules are not included.