9OWB
Human WRN helicase in complex with allosteric ligand Compound 6
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 443 | 50480.9 | 4 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Spodoptera frugiperda (fall armyworm) | DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein |
| 2 | CA, E, N, V (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | DA, F, O, W (D, A, B, C) | N-[2-chloro-4-(trifluoromethyl)phenyl]-2-[(10'R)-1-(3-hydroxypyridine-2-carbonyl)-2'-(morpholin-4-yl)-9'-oxo-5',9'-dihydrospiro[piperidine-4,8'-pyrano[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin]-4'(6'H)-yl]acetamide | non-polymer | 703.1 | 4 | Chemie (A1CEX) | |||
| 4 | AA, BA, FA, G, GA... (C, D, A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 24 | Chemie (EDO) | |||
| 5 | EA (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | LA, MA, NA, OA (A, B, C, D) | water | water | 18.0 | 1504 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 201923.6 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 4599.0 | |
| All* | Total formula weight | 206522.6 |
