9OW4
Hedgehog coronavirus ErinCoV-12-19 spike receptor binding domain in complex with hedgehog APN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Aminopeptidase | polymer | 900 | 102756.3 | 2 | UniProt (A0A1S2ZAK1) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) | Erinaceus europaeus (western European hedgehog) | |
| 2 | B, E (B, E) | Amastatin | polymer | 4 | 474.5 | 2 | Streptomyces | ||
| 3 | C, F (C, F) | Spike glycoprotein | polymer | 209 | 23169.2 | 2 | UniProt (U5LMM7) | Betacoronavirus Erinaceus | S glycoprotein,E2,Peplomer protein |
| 4 | G, H, I, J, M... (G, H, I, J, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, Q (K, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 6 | L, R (L, R) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | AA, BA, CA, EA, FA... (C, D, F, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) PubChem (24139) | |||
| 8 | DA, U (D, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 9 | KA, LA, MA, NA (A, C, D, F) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
C, F: 365 - 573 (UniProt: U5LMM7)
| PDB | External Database | Details |
|---|---|---|
| Glu 372 | Asp 372 | conflict |
| Glu 407 | Gln 407 | conflict |
| Ile 412 | Val 412 | conflict |
| Lys 458 | Asn 458 | conflict |
| Gly 474 | Ala 474 | conflict |
| Ser 485 | Asn 485 | conflict |
| Thr 497 | Val 497 | conflict |
| Val 512 | Ile 512 | conflict |
| Val 513 | Ala 513 | conflict |
| Ile 519 | Leu 519 | conflict |
| Thr 536 | Asn 536 | conflict |
| Asn 545 | Lys 545 | conflict |
| Val 548 | Thr 548 | conflict |
| Asn 550 | Glu 550 | conflict |
| - | Gly 551 | deletion |
| Ile 552 | Val 553 | conflict |
| Asn 561 | Lys 562 | conflict |
| Asn 563 | Asp 564 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 252800.2 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5709.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3670.1 | |
| All* | Total formula weight | 262179.7 |
