9OVT
Heteromeric GluA1/A2 in the inactive state, composite map of LBD-TMD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor 1 | polymer | 431 | 48183.2 | 2 | UniProt (P19490) | Rattus norvegicus (Norway rat) | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1 |
| 2 | B, D (B, D) | Glutamate receptor 2 | polymer | 429 | 47751.9 | 2 | UniProt (P19491) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2 |
| 3 | E, F, H, K (A, B, C, D) | {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | non-polymer | 409.3 | 4 | Chemie (ZK1) PubChem (208953) | |||
| 4 | G, I, J (B, C) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) | |||
| 5 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, C: 385 - 815 (UniProt: P19490)
B, D: 392 - 820 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 740 | Asn 758 | conflict |
| Ser 750 | Asn 768 | conflict |
| Val 754 | Leu 772 | conflict |
| Ser 760 | Asn 778 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 392 | Asn 413 | conflict |
| Arg 586 | Gln 607 | conflict |
| Thr 744 | Asn 765 | conflict |
| Pro 745 | Ala 766 | conflict |
| Ser 754 | Asn 775 | conflict |
| Val 758 | Leu 779 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 191870.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1706.0 | |
| All* | Total formula weight | 193576.2 |
