9OTY
DDB1-CRBN with CK1 alpha, SB-405483, and DEG-47: composite map and model submission
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA damage-binding protein 1 | polymer | 830 | 93061.9 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 2 | B (B) | Protein cereblon | polymer | 382 | 43978.6 | 1 | UniProt (Q96SW2) Pfam (PF02190) Pfam (PF03226) | Homo sapiens (human) | |
| 3 | C (C) | Casein kinase I isoform alpha | polymer | 294 | 34682.2 | 1 | UniProt (P48729) Pfam (PF00069) | Homo sapiens (human) | CKI-alpha,CK1 |
| 4 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (B) | N-{2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}benzamide | non-polymer | 363.4 | 1 | Chemie (A1CEH) | |||
| 6 | F (B) | N-[3-(benzyloxy)pyridin-2-yl]-N'-(4-cyano-2-hydroxyphenyl)urea | non-polymer | 360.4 | 1 | Chemie (A1CEG) |
Sequence modifications
A: 1 - 391 (UniProt: Q16531)
A: 710 - 1140 (UniProt: Q16531)
A: 710 - 1140 (UniProt: Q16531)
| PDB | External Database | Details |
|---|---|---|
| Trp 1141 | - | expression tag |
| Ser 1142 | - | expression tag |
| His 1143 | - | expression tag |
| Pro 1144 | - | expression tag |
| Gln 1145 | - | expression tag |
| Phe 1146 | - | expression tag |
| Glu 1147 | - | expression tag |
| Lys 1148 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 171722.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 789.1 | |
| All* | Total formula weight | 172511.8 |
