9OTI
GATOR2 complex bound to arginine sensor CASTOR1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, I, P (A, B, L, T) | GATOR2 complex protein MIOS | polymer | 875 | 98700.4 | 4 | UniProt (Q9NXC5) Pfam (PF21720) Pfam (PF21719) Pfam (PF17034) | Homo sapiens (human) | Missing oocyte meiosis regulator homolog |
| 2 | C, J (C, M) | GATOR complex protein WDR24 | polymer | 790 | 88327.0 | 2 | UniProt (Q96S15) Pfam (PF00400) | Homo sapiens (human) | WD repeat-containing protein 24 |
| 3 | D, K (D, N) | GATOR complex protein WDR59 | polymer | 974 | 109938.4 | 2 | UniProt (Q6PJI9) Pfam (PF00400) Pfam (PF17120) | Homo sapiens (human) | WD repeat-containing protein 59 |
| 4 | E, F, G, L, M... (E, F, G, O, P...) | Nucleoporin SEH1 | polymer | 360 | 39700.6 | 6 | UniProt (Q96EE3) Pfam (PF00400) | Homo sapiens (human) | GATOR2 complex protein SEH1,Nup107-160 subcomplex subunit SEH1,SEC13-like protein |
| 5 | H, O (H, R) | Protein SEC13 homolog | polymer | 322 | 35578.4 | 2 | UniProt (P55735) Pfam (PF00400) | Homo sapiens (human) | GATOR complex protein SEC13,SEC13-like protein 1,SEC13-related protein |
| 6 | Q, R (U, V) | Cytosolic arginine sensor for mTORC1 subunit 1 | polymer | 329 | 36249.2 | 2 | UniProt (Q8WTX7) Pfam (PF18700) Pfam (PF13840) Pfam (PF21389) | Homo sapiens (human) | Cellular arginine sensor for mTORC1 protein 1,GATS-like protein 3 |
| 7 | AA, BA, CA, DA, EA... (C, D, L, M, N...) | ZINC ION | non-polymer | 65.4 | 29 | Chemie (ZN) |
Sequence modifications
U, V: 1 - 329 (UniProt: Q8WTX7)
| PDB | External Database | Details |
|---|---|---|
| Ala 111 | Ser 111 | engineered mutation |
| Ala 304 | Asp 304 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 1173191.0 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 1896.9 | |
| All* | Total formula weight | 1175087.9 |
