9OT8
Crystal structure of Galectin-3 bound to FN3con-9 and FN3con-41, a cooperative binder that recognises the Galectin-3-FN3con-9 interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FN3con-9 - FN3con-41 fusion,Galectin-3 | polymer | 403 | 42015.9 | 1 | UniProt (P17931) | synthetic construct | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | B (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 1 - 216 (PDB: 9OT8)
A: 261 - 400 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Gly 217 | - | linker |
| Gly 218 | - | linker |
| Gly 219 | - | linker |
| Ser 220 | - | linker |
| Gly 221 | - | linker |
| Gly 222 | - | linker |
| Ser 223 | - | linker |
| Gly 224 | - | linker |
| Gly 225 | - | linker |
| Asp 226 | - | linker |
| Gly 227 | - | linker |
| Gly 228 | - | linker |
| Gly 229 | - | linker |
| Ser 230 | - | linker |
| Gly 231 | - | linker |
| Asp 232 | - | linker |
| Gly 233 | - | linker |
| Gly 234 | - | linker |
| Ser 235 | - | linker |
| Gly 236 | - | linker |
| Ser 237 | - | linker |
| Gly 238 | - | linker |
| Ser 239 | - | linker |
| Gly 240 | - | linker |
| Gly 241 | - | linker |
| Gly 242 | - | linker |
| Gly 243 | - | linker |
| Asp 244 | - | linker |
| Ser 245 | - | linker |
| Gly 246 | - | linker |
| Ser 247 | - | linker |
| Ser 248 | - | linker |
| Gly 249 | - | linker |
| Gly 250 | - | linker |
| Ser 251 | - | linker |
| Gly 252 | - | linker |
| Ser 253 | - | linker |
| Gly 254 | - | linker |
| Gly 255 | - | linker |
| Gly 256 | - | linker |
| Gly 257 | - | linker |
| Ser 258 | - | linker |
| His 259 | - | linker |
| Met 260 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 401 | - | expression tag |
| Lys 402 | - | expression tag |
| Leu 403 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42015.9 | |
| All* | Total formula weight | 42015.9 |
