9ORE
CryoEM structure of 4F11 Fab bound to stabilized MPV-2c HMPV preF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fusion glycoprotein F0 | polymer | 437 | 47566.2 | 1 | UniProt (C6F440) Pfam (PF00523) UniProt (by SIFTS) (Q6WB98) | human metapneumovirus | |
| 2 | B (B) | Fusion glycoprotein F0 | polymer | 438 | 47679.3 | 1 | UniProt (Q8B9P3) Pfam (PF00523) UniProt (by SIFTS) (Q6WB98) | human metapneumovirus | |
| 3 | C (C) | Fusion glycoprotein F0 | polymer | 439 | 47836.5 | 1 | UniProt (Q8B9P3) Pfam (PF00523) UniProt (by SIFTS) (Q6WB98) | human metapneumovirus | |
| 4 | D (H) | 4F11 Heavy Chain | polymer | 123 | 13728.4 | 1 | Homo sapiens (human) | ||
| 5 | E (L) | 4F11 Light Chain | polymer | 113 | 12388.0 | 1 | Homo sapiens (Human) | ||
| 6 | F (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | G (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 8 | H, I, J (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A: 20 - 467 (UniProt: C6F440)
B: 19 - 467 (UniProt: Q8B9P3)
C: 19 - 467 (UniProt: Q8B9P3)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 90 | deletion |
| - | Arg 91 | deletion |
| - | Glu 92 | deletion |
| - | Glu 93 | deletion |
| - | Gln 94 | deletion |
| - | Ile 95 | deletion |
| - | Glu 96 | deletion |
| - | Asn 97 | deletion |
| - | Pro 98 | deletion |
| - | Arg 99 | deletion |
| - | Gln 100 | deletion |
| - | Ser 101 | deletion |
| Arg 112 | Val 112 | conflict |
| Glu 209 | Asp 209 | conflict |
| Ile 231 | Val 231 | conflict |
| Asn 368 | His 368 | conflict |
| Pro 453 | Glu 453 | conflict |
| Asn 468 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| - | Ala 90 | deletion |
| - | Arg 91 | deletion |
| - | Glu 92 | deletion |
| - | Glu 93 | deletion |
| - | Gln 94 | deletion |
| - | Ile 95 | deletion |
| - | Glu 96 | deletion |
| - | Asn 97 | deletion |
| - | Pro 98 | deletion |
| - | Arg 99 | deletion |
| - | Gln 100 | deletion |
| - | Ser 101 | deletion |
| Arg 112 | Val 112 | conflict |
| Glu 209 | Asp 209 | conflict |
| Ile 231 | Val 231 | conflict |
| Asn 368 | His 368 | conflict |
| Pro 453 | Glu 453 | conflict |
| Asn 468 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| - | Ala 90 | deletion |
| - | Arg 91 | deletion |
| - | Glu 92 | deletion |
| - | Glu 93 | deletion |
| - | Gln 94 | deletion |
| - | Ile 95 | deletion |
| - | Glu 96 | deletion |
| - | Asn 97 | deletion |
| - | Pro 98 | deletion |
| - | Arg 99 | deletion |
| - | Gln 100 | deletion |
| Arg 90 | Ser 101 | conflict |
| Arg 112 | Val 112 | conflict |
| Glu 209 | Asp 209 | conflict |
| Ile 231 | Val 231 | conflict |
| Asn 368 | His 368 | conflict |
| Pro 453 | Glu 453 | conflict |
| Asn 468 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 169198.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 170872.9 |
