9OO1
Influenza A Virus Group 2 Hemagglutinin (H7, Strain SH13) in Complex with a Potent Small-Molecule Entry Inhibitor ING-16-36
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Hemagglutinin HA1 | polymer | 338 | 36809.7 | 3 | UniProt (A0A067Y6L0) UniProt (by SIFTS) (A0A8E4VQE2) | Influenza A virus | |
| 2 | D, E, F (D, E, F) | Hemagglutinin HA2 | polymer | 172 | 19850.8 | 3 | UniProt (A0A067Y6L0) UniProt (by SIFTS) (A0A8E4QKM0) | Influenza A virus | |
| 3 | G, H, I (G, H, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | J, K, L, M, O... (A, B, C, D, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 5 | N, Q, S (B, C, D) | (2M,4S)-2-(2-chloropyridin-4-yl)-N-cyclohexyl-5,7-dimethylimidazo[1,2-a]pyrimidin-3-amine | non-polymer | 355.9 | 3 | Chemie (A1CC3) |
Sequence modifications
A, B, C: -17 - 320 (UniProt: A0A067Y6L0)
D, E, F: 1 - 172 (UniProt: A0A067Y6L0)
| PDB | External Database | Details |
|---|---|---|
| Cys 20 | Thr 38 | conflict |
| Ser 128 | Ala 146 | conflict |
| Val 205 | Ala 223 | conflict |
| Tyr 274 | His 292 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 47 | Gln 386 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 169981.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1759.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3058.5 | |
| All* | Total formula weight | 174799.5 |
