9OMT
X-ray structure of paraoxon (POX)-inhibited human acetylcholinesterase (hAChE) in complex with bis-oxime reactivator LG-1922
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) | Homo sapiens (human) | AChE |
| 2 | C, H (A, B) | DIETHYL PHOSPHONATE | non-polymer | 138.1 | 2 | Chemie (DEP) | |||
| 3 | D, I (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | F, J (A, B) | (2E)-2-(hydroxyimino)-N-{3-[(3R)-3-(2-{[(2E)-2-(hydroxyimino)acetyl]amino}ethyl)piperidin-1-yl]propyl}acetamide | non-polymer | 327.4 | 2 | Chemie (A1CDA) | |||
| 6 | G, K (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1333.4 | |
| All* | Total formula weight | 121909.4 |
