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9OLE

Crystal Structure of PI5P4KIIAlpha complex with 066ATZ

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphapolymer37743114.71UniProt (P48426)
Pfam (PF01504)
Homo sapiens (human)1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-Phosphate 4-Kinase,PI5P4Kalpha,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PI(5)P 4-kinase type II alpha,PIP4KII-alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha
2B, C, D
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
3E
(A)
(7S)-8-cyclopentyl-5-methyl-7-[(pyridin-2-yl)methyl]-2-{[5-(1H-tetrazol-5-yl)-1,3-thiazol-2-yl]amino}-7,8-dihydropteridin-6(5H)-onenon-polymer489.61Chemie (A1CCL)
4F
(A)
waterwater18.0197Chemie (HOH)
Sequence modifications
A: 33 - 405 (UniProt: P48426)
PDBExternal DatabaseDetails
Gly 29-expression tag
Ser 30-expression tag
His 31-expression tag
Met 32-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43114.7
Non-Polymers*Number of molecules4
Total formula weight777.7
All*Total formula weight43892.4
*Water molecules are not included.

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PDB entries from 2026-07-29

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