9OLC
Crystal structure of PPARg ligand-binding domain in complex with NCoR1 peptide and FTX-6746
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peroxisome proliferator-activated receptor gamma | polymer | 278 | 31721.8 | 4 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | E, F, G, H (E, F, G, H) | Nuclear receptor corepressor 1 peptide | polymer | 13 | 1487.8 | 4 | UniProt (O75376) | Homo sapiens (human) | N-CoR,N-CoR1 |
| 3 | I, J, K (A, B, C) | (3P)-4-chloro-3-(5,7-difluoro-4-oxo-1,4-dihydroquinolin-2-yl)benzonitrile | non-polymer | 316.7 | 3 | Chemie (A1CCT) PubChem (164916759) | |||
| 4 | L, M, N (A, B, C) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 231 - 505 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Ser 228 | - | expression tag |
| Asn 229 | - | expression tag |
| Ala 230 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 132838.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 950.1 | |
| All* | Total formula weight | 133788.4 |
