9OKJ

Cryo-EM structure of human SV2A in complex with padsevonil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Synaptic vesicle glycoprotein 2A	polymer	604	67822.2	1	Pfam (PF00083) Pfam (PF23894) Pfam (PF07690) UniProt (by SIFTS) (Q7L0J3)	Homo sapiens
2	B, C (A)	(4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one	non-polymer		432.8	2	Chemie (X3U)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	67822.2
Non-Polymers*	Number of molecules	2
	Total formula weight	865.6
All*	Total formula weight	68687.8

*Water molecules are not included.