9OJO
Crystal structure of TNF alpha in complex with compound 1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Tumor necrosis factor | polymer | 158 | 17501.9 | 3 | UniProt (P01375) | Homo sapiens (human) | Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a |
| 2 | D (B) | 2-{5-[(1S,10S)-1-phenyl-1,2,3,4-tetrahydropyrido[1,2-a][1,3]benzimidazol-8-yl]pyrimidin-2-yl}propan-2-ol | non-polymer | 384.5 | 1 | Chemie (A1CB1) | |||
| 3 | E, F, G (A, B, C) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52505.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.5 | |
| All* | Total formula weight | 52890.0 |
