9OIN
The von Hippel Lindau-ElonginB-ElonginC (VCB) complex with fragment 13
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | Elongin-B | polymer | 104 | 11852.4 | 4 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 2 | B (B) | Elongin-C | polymer | 98 | 11135.6 | 1 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 3 | C, F, I, L (C, F, I, L) | von Hippel-Lindau disease tumor suppressor | polymer | 180 | 20833.5 | 4 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | Protein G7,pVHL |
| 4 | E, H, K (E, H, K) | Elongin-C | polymer | 98 | 11031.7 | 3 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 5 | M (L) | 1-(propan-2-yl)-4-[(pyridin-2-yl)methyl]piperazine | non-polymer | 219.3 | 1 | Chemie (A1CBJ) PubChem (1531090) | Homo sapiens | ||
| 6 | N, O, P, Q, R (A, F, J, K, L) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
B: 17 - 112 (UniProt: Q15369)
C, F, I, L: 54 - 213 (UniProt: P40337)
E, H, K: 17 - 112 (UniProt: Q15369)
| PDB | External Database | Details |
|---|---|---|
| Met 15 | - | initiating methionine |
| Gly 16 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 34 | - | expression tag |
| Gly 35 | - | expression tag |
| Ser 36 | - | expression tag |
| Ser 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| His 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Ser 45 | - | expression tag |
| Gly 46 | - | expression tag |
| Leu 47 | - | expression tag |
| Val 48 | - | expression tag |
| Pro 49 | - | expression tag |
| Arg 50 | - | expression tag |
| Gly 51 | - | expression tag |
| Ser 52 | - | expression tag |
| His 53 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 15 | - | initiating methionine |
| Gly 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 174974.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 219.3 | |
| All* | Total formula weight | 175193.6 |
