9OGA
Cryo-EM structure of human full-length XPO1 conjugated with selinexor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Exportin-1 | polymer | 1073 | 123662.5 | 1 | UniProt (O14980) Pfam (PF03810) Pfam (PF08389) Pfam (PF18777) Pfam (PF18784) Pfam (PF18787) Pfam (PF08767) | Homo sapiens (human) | Exp1,Chromosome region maintenance 1 protein homolog |
| 2 | B (A) | selinexor, bound form | non-polymer | 445.3 | 1 | Chemie (V6A) |
Sequence modifications
A: 1 - 1071 (UniProt: O14980)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 123662.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.3 | |
| All* | Total formula weight | 124107.8 |
