9OFS

Crystal structure of the human IGA2m2 FC fragment-FC-alpha receptor (CD89) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Immunoglobulin heavy constant alpha 2	polymer	214	23287.5	1	UniProt (P01877) Pfam (PF00047) Pfam (PF07654)	Homo sapiens (human)	Ig alpha-2 chain C region,Ig alpha-2 chain C region BUT,Ig alpha-2 chain C region LAN
2	B (C)	Immunoglobulin alpha Fc receptor	polymer	207	23615.7	1	UniProt (P24071) Pfam (PF00047)	Homo sapiens (human)	IgA Fc receptor
3	C (G)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G48068RF)
4	D, F, G, H (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG) PubChem (24139)
5	E (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)
6	I, J (A, C)	water	water		18.0	166	Chemie (HOH)

Sequence modifications

A: 241 - 454 (UniProt: P01877)

PDB	External Database	Details
Leu 451	Met 319	conflict
Lys 454	Ser 322	conflict

C: 1 - 195 (UniProt: P24071)

PDB	External Database	Details
Ala 196	-	expression tag
Ile 197	-	expression tag
Asp 198	-	expression tag
Gly 199	-	expression tag
Arg 200	-	expression tag
Ala 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46903.2
Branched	Number of molecules	1
	Total formula weight	748.7
Non-Polymers*	Number of molecules	5
	Total formula weight	920.3
All*	Total formula weight	48572.2

*Water molecules are not included.