Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein cereblon | polymer | 111 | 12309.1 | 4 | UniProt (Q96SW2) Pfam (PF03226) | Homo sapiens (human) | |
| 2 | E, G, I, K (A, B, C, D) | (1P)-1-[(4S)-8H-spiro[furo[2,3-c]imidazo[1,2-a]pyridine-7,4'-piperidin]-3-yl]pyrimidine-2,4(1H,3H)-dione | non-polymer | 339.3 | 4 | Chemie (A1CAW) | |||
| 3 | F, H, J, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 319 - 426 (UniProt: Q96SW2)
| PDB | External Database | Details |
|---|---|---|
| Gly 316 | - | expression tag |
| Pro 317 | - | expression tag |
| Ser 318 | - | expression tag |
| Ser 322 | Cys 322 | conflict |
| Ser 343 | Cys 343 | conflict |
| Ser 366 | Cys 366 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49236.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1619.0 | |
| All* | Total formula weight | 50855.3 |
