9OD9
Structure of disulfide-stabilized IL-18 variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-18 | polymer | 166 | 19163.5 | 1 | UniProt (Q14116) Pfam (PF00340) | Homo sapiens (human) | IL-18,Iboctadekin,Interferon gamma-inducing factor,IFN-gamma-inducing factor,Interleukin-1 gamma,IL-1 gamma |
| 2 | B (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 37 - 193 (UniProt: Q14116)
| PDB | External Database | Details |
|---|---|---|
| Ser 74 | Cys 74 | conflict |
| Ser 104 | Cys 104 | conflict |
| Ser 112 | Cys 112 | conflict |
| Cys 162 | Ala 162 | conflict |
| Ser 163 | Cys 163 | conflict |
| Cys 185 | Ile 185 | conflict |
| Gly 194 | - | expression tag |
| Gly 195 | - | expression tag |
| Gly 196 | - | expression tag |
| Glu 197 | - | expression tag |
| Asn 198 | - | expression tag |
| Leu 199 | - | expression tag |
| Tyr 200 | - | expression tag |
| Phe 201 | - | expression tag |
| Gln 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19163.5 | |
| All* | Total formula weight | 19163.5 |
