9OD2

Cryo-EM structure of modified Zika virus E protein dimer complexed with a neutralizing antibody SMZAb2 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, H)	SMZAb2 Heavy chain	polymer	126	13567.0	2		Homo sapiens (human)
2	B, D (D, L)	SMZAb2 Light chain	polymer	110	11588.9	2		Homo sapiens (human)
3	E, F (A, B)	Envelope protein E	polymer	434	47297.3	2	UniProt (A0A024B7W1)	Zika virus

Sequence modifications

A, B: 0 - 405 (UniProt: A0A024B7W1)

PDB	External Database	Details
Arg -19	-	expression tag
Ser -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Gly -15	-	expression tag
Glu -14	-	expression tag
Gln -13	-	expression tag
Lys -12	-	expression tag
Leu -11	-	expression tag
Ile -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Glu -7	-	expression tag
Asp -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Cys 5	Gly 295	engineered mutation
Cys 102	Gly 392	engineered mutation
Gly 406	-	expression tag
Thr 407	-	expression tag
Gly 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	144906.5
All*	Total formula weight	144906.5

*Water molecules are not included.