9OCW
A constitutively active construct of eukaryotic elongation factor 2 kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calmodulin-1,Eukaryotic elongation factor 2 kinase | polymer | 605 | 68885.9 | 1 | UniProt (P0DP23) UniProt (O00418) Pfam (PF13499) Pfam (PF02816) | Homo sapiens (human) | eEF-2 kinase,eEF-2K,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase |
| 2 | B, C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | E, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | G, H, I (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | J (A) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A: 3 - 74 (UniProt: P0DP23)
A: 77 - 364 (UniProt: O00418)
A: 371 - 606 (UniProt: O00418)
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| Gly 75 | - | linker |
| Gly 76 | - | linker |
A: 371 - 606 (UniProt: O00418)
| PDB | External Database | Details |
|---|---|---|
| Gly 365 | - | linker |
| Gly 366 | - | linker |
| Gly 367 | - | linker |
| Gly 368 | - | linker |
| Gly 369 | - | linker |
| Gly 370 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 68885.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1072.9 | |
| All* | Total formula weight | 69958.8 |
