9OCN
PC68_L31_570 Fab in complex with HIV-1 Env BG505 SOSIP.664 and RM20A3 Fab
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (A, C, D) | HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120 | polymer | 516 | 57946.0 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 | |
| 2 | B, H, N (B, E, F) | Transmembrane protein gp41 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S5) | Human immunodeficiency virus 1 | |
| 3 | C, I, O (H, G, I) | PC68_L31_570 heavy chain Fv | polymer | 127 | 14162.8 | 3 | Homo sapiens (human) | ||
| 4 | D, J, P (L, J, K) | PC68_L31_570 light chain Fv | polymer | 104 | 10821.0 | 3 | Homo sapiens (human) | ||
| 5 | E, K, Q (M, O, P) | RM20A3 heavy chain Fv | polymer | 125 | 13511.1 | 3 | Macaca mulatta | ||
| 6 | F, L, R (N, Q, R) | RM20A3 light chain Fv | polymer | 110 | 11627.7 | 3 | Macaca mulatta | ||
| 7 | AA, BA, CA, EA, GA... (a, b, c, e, g...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB | |||
| 8 | FA, T, Z (f, T, Z) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB | |||
| 9 | DA, JA, X (d, j, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB | |||
| 10 | AB, BB, CB, DB, EB... (C, E, A, D, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 42 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, C, D: 31 - 508 (UniProt: Q2N0S6)
B, E, F: 512 - 664 (UniProt: Q2N0S5)
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Arg 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Cys 4 | - | expression tag |
| Cys 5 | - | expression tag |
| Val 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Cys 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Phe 14 | - | expression tag |
| Val 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Gln 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Ile 21 | - | expression tag |
| His 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Phe 25 | - | expression tag |
| Arg 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Arg 30 | - | expression tag |
| Asn 332 | Thr 330 | engineered mutation |
| Cys 501 | Ala 498 | engineered mutation |
| Arg 509 | - | expression tag |
| Arg 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | engineered mutation |
| Cys 605 | Thr 602 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 375645.1 | |
| Branched | Number of molecules | 18 |
| Total formula weight | 9098.5 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 9290.7 | |
| All* | Total formula weight | 394034.3 |
