9OBO
Crystal structure of Mycobacterium tuberculosis isocitrate lyase 2 fixed in the apo form with disulfide bonds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isocitrate lyase 2 | polymer | 766 | 85411.6 | 4 | UniProt (Q8VJU4) Pfam (PF00463) | Mycobacterium tuberculosis CDC1551 | ICL2,Isocitrase,Isocitratase |
| 2 | E, I, J, L (A, B, C, D) | SUCCINIC ACID | non-polymer | 118.1 | 4 | Chemie (SIN) PubChem (1110) | |||
| 3 | F, G, H, K (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 715 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 766 (UniProt: Q8VJU4)
| PDB | External Database | Details |
|---|---|---|
| Cys 635 | Gln 635 | engineered mutation |
| Cys 708 | Val 708 | engineered mutation |
| Cys 734 | Val 734 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 341646.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 720.6 | |
| All* | Total formula weight | 342367.2 |
