9O9J
Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with G51D mutaion in SNCA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Alpha-synuclein | polymer | 140 | 14534.1 | 2 | UniProt (P37840) Pfam (PF01387) | Homo sapiens (human) | Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP |
| 2 | B, D (B, E) | unassigned peptide | polymer | 9 | 784.0 | 2 | Homo sapiens (human) | ||
| 3 | E, F (A, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 140 (UniProt: P37840)
| PDB | External Database | Details |
|---|---|---|
| Asp 51 | Gly 51 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30636.2 | |
| All* | Total formula weight | 30636.2 |
