9O95

Cryo-EM structure of CLC-ec1 at pH 7.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	H(+)/Cl(-) exchange transporter ClcA	polymer	489	52115.4	2	UniProt (P37019) Pfam (PF00654)	Escherichia coli	ClC-ec1
2	C, D, E, F (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)

Sequence modifications

A, B: 1 - 468 (UniProt: P37019)

PDB	External Database	Details
Lys 469	-	expression tag
Gly 470	-	expression tag
Ser 471	-	expression tag
Gly 472	-	expression tag
Thr 473	-	expression tag
Leu 474	-	expression tag
Val 475	-	expression tag
Pro 476	-	expression tag
Arg 477	-	expression tag
Gly 478	-	expression tag
Ser 479	-	expression tag
Gly 480	-	expression tag
Gly 481	-	expression tag
Leu 482	-	expression tag
Glu 483	-	expression tag
His 484	-	expression tag
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104230.7
Non-Polymers*	Number of molecules	4
	Total formula weight	141.8
All*	Total formula weight	104372.5

*Water molecules are not included.