9O8M
Ab1983 in complex with HIV-1 Env variant WIN332
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Antibody Ab1983 Heavy Chain variable fragment | polymer | 123 | 13425.9 | 2 | Homo sapiens (human) | ||
| 2 | B, D (B, D) | Ab1983 Light Chain variable fragment | polymer | 116 | 12127.3 | 2 | Homo sapiens (human) | ||
| 3 | E, G, I (K, E, I) | Envelope glycoprotein gp160 | polymer | 479 | 53963.4 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 | Env polyprotein |
| 4 | F, H, J (J, F, L) | Envelope glycoprotein gp160 of Transmembrane protein gp41 | polymer | 153 | 17134.3 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 | TM, Glycoprotein 41, gp41 |
| 5 | K, P (G, P) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 6 | L, Q, U (H, Q, U) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 7 | M, O, R, T, V... (M, O, R, T, V...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 8 | N, S, W (N, S, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 9 | AA, BA, CA, DA, EA... (K, E, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 22 | Chemie (NAG) |
Sequence modifications
K, E, I: 33 - 513 (UniProt: Q2N0S6)
J, F, L: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Tyr 134 | Val 133 | conflict |
| Ala 135 | Thr 134 | conflict |
| Pro 136 | Asn 135 | conflict |
| Leu 138 | Ile 137 | conflict |
| Leu 139 | Thr 138 | conflict |
| Ser 140 | Asp 139 | conflict |
| Asn 149 | Asp 140 | conflict |
| Gln 156 | Asn 147 | conflict |
| Ile 271 | Met 270 | conflict |
| Leu 288 | Phe 287 | conflict |
| Val 304 | Arg 303 | conflict |
| Tyr 319 | Ala 316 | conflict |
| Phe 320 | Thr 317 | conflict |
| Met 328 | Gln 326 | conflict |
| Gln 332 | Thr 330 | conflict |
| Gln 363 | Asn 361 | conflict |
| Val 415 | Thr 412 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | Glu 506 | conflict |
| Arg 510 | Lys 507 | conflict |
| Arg 512 | Ala 509 | conflict |
| Arg 513 | Val 510 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 516 | conflict |
| Pro 559 | Ile 556 | conflict |
| Pro 561 | Ala 558 | conflict |
| Asp 568 | Leu 565 | conflict |
| His 570 | Val 567 | conflict |
| His 585 | Arg 582 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 264399.5 | |
| Branched | Number of molecules | 14 |
| Total formula weight | 8259.6 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4866.6 | |
| All* | Total formula weight | 277525.7 |
