9O7P
Crystal structure of human adenosine kinase (ADK) in complex with inhibitor BKI-1817
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2 of Adenosine kinase | polymer | 465 | 52372.4 | 1 | UniProt (P55263) Pfam (PF00294) | Homo sapiens (human) | AK,Adenosine 5'-phosphotransferase |
| 2 | B, S, T (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 3 | C, E, F, G, H... (A) | SULFATE ION | non-polymer | 96.1 | 15 | Chemie (SO4) | |||
| 4 | D (A) | (6M)-6-{4-amino-1-[(1-methylpiperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}quinolin-2(1H)-one | non-polymer | 389.5 | 1 | Chemie (A1B96) PubChem (166643538) | |||
| 5 | U (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 1 - 345 (UniProt: P55263)
| PDB | External Database | Details |
|---|---|---|
| Met -119 | - | initiating methionine |
| Ala -118 | - | expression tag |
| His -117 | - | expression tag |
| His -116 | - | expression tag |
| His -115 | - | expression tag |
| His -114 | - | expression tag |
| His -113 | - | expression tag |
| His -112 | - | expression tag |
| Met -111 | - | expression tag |
| Lys -110 | - | expression tag |
| Ser -109 | - | expression tag |
| Asp -108 | - | expression tag |
| Ser -107 | - | expression tag |
| Glu -106 | - | expression tag |
| Val -105 | - | expression tag |
| Asn -104 | - | expression tag |
| Gln -103 | - | expression tag |
| Glu -102 | - | expression tag |
| Ala -101 | - | expression tag |
| Lys -100 | - | expression tag |
| Pro -99 | - | expression tag |
| Glu -98 | - | expression tag |
| Val -97 | - | expression tag |
| Lys -96 | - | expression tag |
| Pro -95 | - | expression tag |
| Glu -94 | - | expression tag |
| Val -93 | - | expression tag |
| Lys -92 | - | expression tag |
| Pro -91 | - | expression tag |
| Glu -90 | - | expression tag |
| Thr -89 | - | expression tag |
| His -88 | - | expression tag |
| Ile -87 | - | expression tag |
| Asn -86 | - | expression tag |
| Leu -85 | - | expression tag |
| Lys -84 | - | expression tag |
| Val -83 | - | expression tag |
| Ser -82 | - | expression tag |
| Asp -81 | - | expression tag |
| Gly -80 | - | expression tag |
| Ser -79 | - | expression tag |
| Ser -78 | - | expression tag |
| Glu -77 | - | expression tag |
| Ile -76 | - | expression tag |
| Phe -75 | - | expression tag |
| Phe -74 | - | expression tag |
| Lys -73 | - | expression tag |
| Ile -72 | - | expression tag |
| Lys -71 | - | expression tag |
| Lys -70 | - | expression tag |
| Thr -69 | - | expression tag |
| Thr -68 | - | expression tag |
| Pro -67 | - | expression tag |
| Leu -66 | - | expression tag |
| Arg -65 | - | expression tag |
| Arg -64 | - | expression tag |
| Leu -63 | - | expression tag |
| Met -62 | - | expression tag |
| Glu -61 | - | expression tag |
| Ala -60 | - | expression tag |
| Phe -59 | - | expression tag |
| Ala -58 | - | expression tag |
| Lys -57 | - | expression tag |
| Arg -56 | - | expression tag |
| Gln -55 | - | expression tag |
| Gly -54 | - | expression tag |
| Lys -53 | - | expression tag |
| Glu -52 | - | expression tag |
| Met -51 | - | expression tag |
| Asp -50 | - | expression tag |
| Ser -49 | - | expression tag |
| Leu -48 | - | expression tag |
| Arg -47 | - | expression tag |
| Phe -46 | - | expression tag |
| Leu -45 | - | expression tag |
| Tyr -44 | - | expression tag |
| Asp -43 | - | expression tag |
| Gly -42 | - | expression tag |
| Ile -41 | - | expression tag |
| Arg -40 | - | expression tag |
| Ile -39 | - | expression tag |
| Gln -38 | - | expression tag |
| Ala -37 | - | expression tag |
| Asp -36 | - | expression tag |
| Gln -35 | - | expression tag |
| Thr -34 | - | expression tag |
| Pro -33 | - | expression tag |
| Glu -32 | - | expression tag |
| Asp -31 | - | expression tag |
| Leu -30 | - | expression tag |
| Asp -29 | - | expression tag |
| Met -28 | - | expression tag |
| Glu -27 | - | expression tag |
| Asp -26 | - | expression tag |
| Asn -25 | - | expression tag |
| Asp -24 | - | expression tag |
| Ile -23 | - | expression tag |
| Ile -22 | - | expression tag |
| Glu -21 | - | expression tag |
| Ala -20 | - | expression tag |
| His -19 | - | expression tag |
| Arg -18 | - | expression tag |
| Glu -17 | - | expression tag |
| Gln -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Thr -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Gln -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52372.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1936.8 | |
| All* | Total formula weight | 54309.2 |
