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9O63

Crystal structure of PLK4 and RP1664 complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PLK4polymer27831723.71UniProt (O00444)
Pfam (PF00069)
Homo sapiens (human)Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak
2B, C
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D
(A)
5-cyclopropyl-N~2~-[2,6-difluoro-4-(methanesulfonyl)phenyl]-N~2~-methyl-6-(1-methyl-1H-imidazol-4-yl)-N~4~-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diaminenon-polymer514.61Chemie (A1CAD)
4E
(A)
waterwater18.038Chemie (HOH)
Sequence modifications
A: 2 - 275 (UniProt: O00444)
PDBExternal DatabaseDetails
Ser 0-expression tag
Leu 1-expression tag
Glu 276-expression tag
Gly 277-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31723.7
Non-Polymers*Number of molecules3
Total formula weight706.7
All*Total formula weight32430.3
*Water molecules are not included.

250835

PDB entries from 2026-03-18

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