9O3D
Crystal structure of broadly neutralizing antibody HEPC108 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, H, I (A, E, H, I) | HEPC108 Fab Heavy Chain | polymer | 237 | 25248.4 | 4 | Homo sapiens (human) | ||
| 2 | B, F, J, L (B, F, J, L) | HEPC108 Fab Light Chain | polymer | 216 | 23725.2 | 4 | Homo sapiens (human) | ||
| 3 | C, D, G, K (C, D, G, K) | Envelope Glycoprotein E2 | polymer | 262 | 28946.5 | 4 | UniProt (X4ZFZ7) | Hepatitis C virus subtype 1b | |
| 4 | M, P, S, V, W... (M, P, S, V, W...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | N, R, U (N, R, U) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | O (O) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G34442SS) | |||
| 7 | Q, T (Q, T) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 8 | Y (Y) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 9 | EA, KA, NA, OA, Z (D, G, K, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 10 | AA, BA, CA, DA, FA... (C, D, G, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 11 | AB, BB, CB, UA, VA... (I, J, K, A, B...) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 311680.3 | |
| Branched | Number of molecules | 13 |
| Total formula weight | 7949.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3999.8 | |
| All* | Total formula weight | 323629.4 |
