9O38
Transmembrane domains of the human sweet receptor (TAS1R2 + TAS1R3) from Class 3 particles (rigidly fitted from PDB:9NOX and 9NOR)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (B, F) | Taste receptor type 1 member 3,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | polymer | 1128 | 124469.3 | 2 | UniProt (Q7RTX0) UniProt (P63092) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) Pfam (PF00503) | Homo sapiens (human) | Sweet taste receptor T1R3,Adenylate cyclase-stimulating G alpha protein |
| 2 | B (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (E) | Nanobody 35 (NB35) | polymer | 160 | 17352.5 | 1 | Lama glama (llama) | ||
| 5 | E (A) | Taste receptor type 1 member 2 | polymer | 848 | 96239.0 | 1 | UniProt (Q8TE23) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (human) | G-protein coupled receptor 71,Sweet taste receptor T1R2 |
Sequence modifications
B, F: -850 - -19 (UniProt: Q7RTX0)
B, F: 2 - 61 (UniProt: P63092)
B, F: 70 - 225 (UniProt: P63092)
A: 19 - 839 (UniProt: Q8TE23)
| PDB | External Database | Details |
|---|---|---|
| Met -877 | - | expression tag |
| Lys -876 | - | expression tag |
| Thr -875 | - | expression tag |
| Ile -874 | - | expression tag |
| Ile -873 | - | expression tag |
| Ala -872 | - | expression tag |
| Leu -871 | - | expression tag |
| Ser -870 | - | expression tag |
| Tyr -869 | - | expression tag |
| Ile -868 | - | expression tag |
| Phe -867 | - | expression tag |
| Cys -866 | - | expression tag |
| Leu -865 | - | expression tag |
| Val -864 | - | expression tag |
| Phe -863 | - | expression tag |
| Ala -862 | - | expression tag |
| Asp -861 | - | expression tag |
| Tyr -860 | - | expression tag |
| Lys -859 | - | expression tag |
| Asp -858 | - | expression tag |
| Asp -857 | - | expression tag |
| Asp -856 | - | expression tag |
| Asp -855 | - | expression tag |
| Lys -854 | - | expression tag |
| Ala -853 | - | expression tag |
| Ala -852 | - | expression tag |
| Ala -851 | - | expression tag |
| Arg -114 | Cys 757 | conflict |
| Gly -18 | - | linker |
| Gly -17 | - | linker |
| Gly -16 | - | linker |
| Ser -15 | - | linker |
| Gly -14 | - | linker |
| Gly -13 | - | linker |
| Gly -12 | - | linker |
| Ser -11 | - | linker |
| Gly -10 | - | linker |
| Gly -9 | - | linker |
| Gly -8 | - | linker |
| Ser -7 | - | linker |
| Gly -6 | - | linker |
| Gly -5 | - | linker |
| Gly -4 | - | linker |
| Ser -3 | - | linker |
| Gly -2 | - | linker |
| Gly -1 | - | linker |
| Gly 0 | - | linker |
| Ser 1 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asp 46 | Gly 49 | conflict |
| Asn 47 | Glu 50 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 62 | - | linker |
| Gly 63 | - | linker |
| Ser 64 | - | linker |
| Gly 65 | - | linker |
| Gly 66 | - | linker |
| Ser 67 | - | linker |
| Gly 68 | - | linker |
| Gly 69 | - | linker |
| Asp 115 | Ala 249 | conflict |
| Asp 118 | Ser 252 | conflict |
| - | Asn 254 | deletion |
| - | Met 255 | deletion |
| - | Val 256 | deletion |
| - | Ile 257 | deletion |
| - | Arg 258 | deletion |
| - | Glu 259 | deletion |
| - | Asp 260 | deletion |
| - | Asn 261 | deletion |
| - | Gln 262 | deletion |
| - | Thr 263 | deletion |
| Asp 128 | Leu 272 | conflict |
| Gln 226 | - | expression tag |
| Asn 227 | - | expression tag |
| Val 228 | - | expression tag |
| Lys 229 | - | expression tag |
| Phe 230 | - | expression tag |
| Val 231 | - | expression tag |
| Phe 232 | - | expression tag |
| Asp 233 | - | expression tag |
| Ala 234 | - | expression tag |
| Val 235 | - | expression tag |
| Thr 236 | - | expression tag |
| Asp 237 | - | expression tag |
| Ile 238 | - | expression tag |
| Ile 239 | - | expression tag |
| Ile 240 | - | expression tag |
| Lys 241 | - | expression tag |
| Glu 242 | - | expression tag |
| Asn 243 | - | expression tag |
| Leu 244 | - | expression tag |
| Lys 245 | - | expression tag |
| Asp 246 | - | expression tag |
| Cys 247 | - | expression tag |
| Gly 248 | - | expression tag |
| Leu 249 | - | expression tag |
| Phe 250 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Thr -6 | - | expression tag |
| Ile -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Tyr 0 | - | expression tag |
| Ile 1 | - | expression tag |
| Phe 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Phe 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Tyr 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Tyr 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Val 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Tyr 15 | - | expression tag |
| Ala 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Ala 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 407808.3 | |
| All* | Total formula weight | 407808.3 |
