9O1V
Heparanase P6 in complex with fragment J21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heparanase 50 kDa subunit | polymer | 384 | 42986.3 | 1 | UniProt (Q9Y251) | Homo sapiens (human) | |
| 2 | B (B) | Heparanase 8 kDa subunit | polymer | 74 | 8273.5 | 1 | UniProt (Q9Y251) | Homo sapiens (human) | |
| 3 | C (A) | [azanyl(piperidin-1-yl)methylidene]azanium | non-polymer | 128.2 | 1 | Chemie (D86) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F, G, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 160 - 543 (UniProt: Q9Y251)
| PDB | External Database | Details |
|---|---|---|
| Lys 178 | Asn 178 | conflict |
| Ser 195 | Ala 195 | conflict |
| Gly 197 | Leu 197 | conflict |
| Ala 212 | Ser 212 | conflict |
| Asp 219 | Ser 219 | conflict |
| Arg 230 | Leu 230 | conflict |
| Gly 234 | Asp 234 | conflict |
| Lys 244 | Glu 244 | conflict |
| His 248 | Gln 248 | conflict |
| Gly 273 | Arg 273 | conflict |
| Ala 292 | Ser 292 | conflict |
| Leu 307 | Lys 307 | conflict |
| Thr 318 | Ile 318 | conflict |
| Gln 322 | Ser 322 | conflict |
| Leu 327 | Phe 327 | conflict |
| Gly 354 | Leu 354 | conflict |
| Gln 426 | Ser 426 | conflict |
| Asp 427 | Lys 427 | conflict |
| Gln 477 | Lys 477 | conflict |
| His 483 | Leu 483 | conflict |
| Asp 486 | His 486 | conflict |
| Gln 498 | Leu 498 | conflict |
| Lys 512 | Met 512 | conflict |
| Pro 513 | Glu 513 | conflict |
| Ala 530 | Ser 530 | conflict |
| Pro 540 | Ala 540 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51259.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 862.7 | |
| All* | Total formula weight | 52122.5 |
