9O15

Crystal Structure of BCL-2 (G101V) mutant in complex with a stapled BAD BH3 peptide BAD SAHB 4.2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Apoptosis regulator Bcl-2,Bcl-2-like protein 1	polymer	166	19399.6	6	UniProt (P10415) UniProt (Q07817) Pfam (PF02180) Pfam (PF00452)	Homo sapiens (human)	Bcl2-L-1,Apoptosis regulator Bcl-X
2	B, D, F, H, J... (B, D, F, H, J...)	stapled BAD BH3 peptide BAD SAHB 4.2	polymer	23	2781.2	8	UniProt (by SIFTS) (Q92934)	Homo sapiens
3	AA, BA, O, P, Q... (M, N, A, B, C...)	water	water		18.0	473	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 1 - 75 (UniProt: P10415)
A, C, E, G, I, K: 76 - 91 (UniProt: Q07817)
A, C, E, G, I, K: 92 - 207 (UniProt: P10415)

PDB	External Database	Details
Val 101	Gly 101	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	138647.4
All*	Total formula weight	138647.4

*Water molecules are not included.