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9O14

Crystal Structure of BCL-2 in complex with a stapled BAD BH3 peptide BAD SAHB 4.2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Apoptosis regulator Bcl-2,Bcl-2-like protein 1polymer16619357.61UniProt (P10415)
UniProt (Q07817)
Pfam (PF02180)
Pfam (PF00452)
Homo sapiens (human)Bcl2-L-1,Apoptosis regulator Bcl-X
2B
(B)
stapled BAD BH3 peptide BAD SAHB 4.2polymer232781.21UniProt (by SIFTS) (Q92934)Homo sapiens
3C, D
(A)
NICKEL (II) IONnon-polymer58.72Chemie (NI)
4E
(A)
NITRILOTRIACETIC ACIDnon-polymer191.11Chemie (NTA)
5F, G
(A, B)
waterwater18.0104Chemie (HOH)
Sequence modifications
A: 1 - 75 (UniProt: P10415)
A: 76 - 91 (UniProt: Q07817)
A: 92 - 207 (UniProt: P10415)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight22138.8
Non-Polymers*Number of molecules3
Total formula weight308.5
All*Total formula weight22447.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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