9NZD
Crystal structure of AfNth1-K122A mutant bound to Tg-DNA duplex complex in an intermediate state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Endonuclease III | polymer | 209 | 23650.7 | 2 | UniProt (O28581) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) | Archaeoglobus fulgidus | DNA-(apurinic or apyrimidinic site) lyase |
| 2 | B, E (B, E) | DNA (5'-D(*TP*TP*GP*GP*CP*GP*TP*AP*TP*CP*GP*CP*G)-3') | polymer | 13 | 3998.6 | 2 | synthetic construct | ||
| 3 | C, F (C, F) | DNA (5'-D(*AP*CP*GP*CP*GP*AP*(CTG)P*AP*CP*GP*CP*CP*A)-3') | polymer | 13 | 3979.6 | 2 | synthetic construct | ||
| 4 | G, H (A, D) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
| 5 | I, J, K, L, M (A, C, D, E, F) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 209 (UniProt: O28581)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Lys 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 63257.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 703.3 | |
| All* | Total formula weight | 63961.2 |
