9NYQ
Crystal structure of CDK2/CyclinE1 in complex with Cpd 3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 299 | 34127.5 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B (B) | G1/S-specific cyclin-E1 | polymer | 410 | 47136.1 | 1 | UniProt (P24864) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | |
| 3 | C (A) | 4-({4-[(1s,4s)-4-hydroxy-4-methylcyclohexyl]-5-(trifluoromethyl)pyrimidin-2-yl}amino)-N,3-dimethylbenzene-1-sulfonamide | non-polymer | 458.5 | 1 | Chemie (A1B7H) | |||
| 4 | D (B) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81263.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 650.6 | |
| All* | Total formula weight | 81914.3 |
